5-bromo-3-nitro-pyridin-2-amine

Basic Information

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CAS Number

6945-68-2

Molecular Formula

C5H4BrN3O2

Molecular Weight

218.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

207.0 to 212.0 deg-C

Boiling Point

302.9℃ at 760 mmHg

Density

1.9128 (rough estimate)

Flash Point

137℃

Refractive Index

1.6200 (estimate)

SMILES

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C1=C(C=NC(=C1[N+](=O)[O-])N)Br

InChI

InChI=1S/C5H4BrN3O2/c6-3-1-4(9(10)11)5(7)8-2-3/h1-2H,(H2,7,8)

InChIKey

QOOCOFOGYRQPPN-UHFFFAOYSA-N

LogP

2.43890

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

BCP22203
CS-W002231
DTXSID60219611
InChI=1/C5H4BrN3O2/c6-3-1-4(9(10)11)5(7)8-2-3/h1-2H,(H2,7,8
FT-0611146
AKOS001407760
SCHEMBL203876
SR-01000516093-1
5-bromo-3-nitropyridine-2-amine
A9189
5-bromo-3-nitropyridin-2-amine
NS00036856
PB24568
STR06048
5-bromo-3-nitro-pyridin-2-ylamine
SR-01000516093
6945-68-2
Q-103390
EN300-16708
2-Amino-5-bromo-3-nitropyridine
2-Amino-5-bromo-3-nitropyridine;
SR-01000516093-2
AE-848/01509005
HY-W002231
2-amino-5-bromo3-nitropyridine
2-Amino-5-bromo-3-nitropyridine, 97%
2-Pyridinamine, 5-bromo-3-nitro-
5-BROMO-3-NITRO-2-PYRIDINAMINE
NSC 52200
CCG-41239
SY013559

MDL Number

MFCD00047441

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-bromo-3-nitro-pyridin-2-amine (CAS: 6945-68-2)?

5-Bromo-3-nitro-pyridin-2-amine is a crystalline solid with a molecular weight of approximately 225.03 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound is chemically reactive, especially towards nucleophiles and reducing agents, but stable under normal storage conditions.

How is 5-bromo-3-nitro-pyridin-2-amine (CAS: 6945-68-2) typically synthesized?

5-Bromo-3-nitro-pyridin-2-amine can be synthesized via the nitration of 5-bromo-pyridine followed by reduction of the nitro group. Commonly used catalysts include sulfuric acid, and the reaction yields are typically around 70-85%. The process involves controlling temperature and reaction time to achieve high selectivity.

What industries use 5-bromo-3-nitro-pyridin-2-amine (CAS: 6945-68-2)?

5-Bromo-3-nitro-pyridin-2-amine finds application in the pharmaceutical industry as an intermediate in drug synthesis. It is also utilized in the production of certain polymers and as a component in sensor technology. Additionally, it is used in the synthesis of semiconductors due to its electronic properties.

What precautions should be taken when handling 5-bromo-3-nitro-pyridin-2-amine (CAS: 6945-68-2)?

When handling 5-bromo-3-nitro-pyridin-2-amine, proper personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials and contaminated waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.