N-(4-Piperidinyl)-2-pyrimidinamine

Basic Information

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CAS Number

69385-85-9

Molecular Formula

C9H14N4

Molecular Weight

178.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1CNCCC1NC2=NC=CC=N2

InChI

InChI=1S/C9H14N4/c1-4-11-9(12-5-1)13-8-2-6-10-7-3-8/h1,4-5,8,10H,2-3,6-7H2,(H,11,12,13)

InChIKey

HQPSCRCCYZGOIV-UHFFFAOYSA-N

LogP

0.6404999999999995

Topological Polar Surface Area

49.84 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

139

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

69385-85-9
N-(4-piperidinyl)-2-pyrimidinamine
SB42985
CS-W003945
piperidin-4-ylpyrimidin-2-yl-amine
FT-0761186
MFCD09936150
A866847
n-piperidin-4-ylpyrimidin-2-amine
AKOS000177815
N-(Piperidin-4-yl)pyrimidin-2-amine
DTXSID60593241
EN300-7424321
2-(4-Piperidylamino)pyrimidine
HQPSCRCCYZGOIV-UHFFFAOYSA-N
DS-2571
PIPERIDIN-4-YL-PYRIMIDIN-2-YL-AMINE
C76200
SCHEMBL1073617
BB 0238897
N-4-piperidinyl-2-Pyrimidinamine
N-piperidin-4-ylpyrimidin-2-amine
N-(4-piperidyl)pyrimidin-2-amine
2-Pyrimidinamine,N-4-piperidinyl-
0713AC
TRA0085821
ST2413562
BB

MDL Number

MFCD09936150

Customs Code

2933990090

FAQ

What are the physical and chemical properties of N-(4-Piperidinyl)-2-pyrimidinamine (CAS: 69385-85-9)?

N-(4-Piperidinyl)-2-pyrimidinamine is a crystalline solid with a molecular weight of approximately 226.33 g/mol. It is slightly soluble in water and has good solubility in organic solvents like methanol and ethanol. The compound is moderately reactive, particularly towards nucleophiles, and can participate in condensation reactions. It is stable under normal laboratory conditions but should be stored away from strong acids and bases.

How is N-(4-Piperidinyl)-2-pyrimidinamine (CAS: 69385-85-9) typically synthesized?

N-(4-Piperidinyl)-2-pyrimidinamine can be synthesized via a multistep process starting with 2-pyrimidinamine and 4-piperidinecarboxylic acid. The reaction involves the condensation of these two compounds, often catalyzed by an acid or base, to form the target amide. The yield ranges from 60% to 70%, with high selectivity to the desired product.

What industries use N-(4-Piperidinyl)-2-pyrimidinamine (CAS: 69385-85-9)?

N-(4-Piperidinyl)-2-pyrimidinamine is used in pharmaceutical industries for its potential as a drug candidate. It also finds applications in the development of sensors and semiconductors due to its electronic properties. Additionally, it may be utilized in the polymer industry for specific functional applications.

What precautions should be taken when handling N-(4-Piperidinyl)-2-pyrimidinamine (CAS: 69385-85-9)?

When handling N-(4-Piperidinyl)-2-pyrimidinamine, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed information and safety guidelines.