N-(4-Piperidinyl)-2-pyrimidinamine(CAS: 69385-85-9)

N-(4-Piperidinyl)-2-pyrimidinamine is a crystalline solid with a molecular weight of approximately 226.33 g/mol. It is slightly soluble in water and has good solubility in organic solvents like methanol and ethanol. The compound is moderately reactive, particularly towards nucleophiles, and can participate in condensation reactions. It is stable under normal laboratory conditions but should be stored away from strong acids and bases.

N-(4-Piperidinyl)-2-pyrimidinamine can be synthesized via a multistep process starting with 2-pyrimidinamine and 4-piperidinecarboxylic acid. The reaction involves the condensation of these two compounds, often catalyzed by an acid or base, to form the target amide. The yield ranges from 60% to 70%, with high selectivity to the desired product.

N-(4-Piperidinyl)-2-pyrimidinamine is used in pharmaceutical industries for its potential as a drug candidate. It also finds applications in the development of sensors and semiconductors due to its electronic properties. Additionally, it may be utilized in the polymer industry for specific functional applications.

When handling N-(4-Piperidinyl)-2-pyrimidinamine, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed information and safety guidelines.