Imidazo[1,2-a]pyridin-8-ol

Basic Information

View in Editor

CAS Number

69214-22-8

Molecular Formula

C7H6N2O

Molecular Weight

134.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

154-157°

SMILES

View in Editor

C1=CN2C=CN=C2C(=C1)O

InChI

InChI=1S/C7H6N2O/c10-6-2-1-4-9-5-3-8-7(6)9/h1-5,10H

InChIKey

VPUDIWIKGNMSOL-UHFFFAOYSA-N

LogP

1.0398999999999998

Topological Polar Surface Area

37.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

129

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AKOS005071339
CS-W005945
H-IMIDAZO[1,2-A]PYRIDINE-8-OL
A836395
SCHEMBL1041231
8-Hydroxyimidazo[1,2-a]pyridine
MFCD06496222
8-hydroxy-imidazo[1,2-a]pyridine
BP-20258
120190-06-9
J-521494
FT-0680694
VPUDIWIKGNMSOL-UHFFFAOYSA-N
8X-0841
Z1201623531
FT-0706414
imidazo[1,2-a]pyridin-8-ol
Imidazo[1,2-a]pyridin-8-ol (9CI)
Imidazo[1,2-a]pyridin-8-ol, AldrichCPR
8-imidazo[1,2-a]pyridinol
Imidazo[1,2-a]pyridin-8-ol, conjugate monoacid
69214-22-8
EN300-257492
SY038285
Imidazo[1,2-a]pyridin-8-ol
8-hydroxy-imidazopyridine
hydroxy-8 imidazo<1,2-a>pyridine
cis-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-1-phenylcyclopropanecarboxylic acid
imidazoapyridinol
Imidazo[1,2-a]pyridine-8-ol
EBD16977

MDL Number

MFCD06496222

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Imidazo[1,2-a]pyridin-8-ol (CAS: 69214-22-8)?

Imidazo[1,2-a]pyridin-8-ol is a crystalline solid with a molecular weight of approximately 195.21 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol. The compound is known for its reactivity in aromatic substitution reactions and its stability under normal conditions.

How is Imidazo[1,2-a]pyridin-8-ol (CAS: 69214-22-8) typically synthesized?

Imidazo[1,2-a]pyridin-8-ol can be synthesized via the condensation of 2-methylpyridine and cyanamide, followed by hydrogenation to reduce the nitrile group. Commonly used catalysts include palladium on carbon, and the yield can be up to 85% with good selectivity.

What industries use Imidazo[1,2-a]pyridin-8-ol (CAS: 69214-22-8)?

Imidazo[1,2-a]pyridin-8-ol is primarily used in the pharmaceutical industry for the development of potential antitumor agents. It also finds applications in the synthesis of functional materials for sensors and semiconductors.

What precautions should be taken when handling Imidazo[1,2-a]pyridin-8-ol (CAS: 69214-22-8)?

When handling Imidazo[1,2-a]pyridin-8-ol, it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. Work in a fume hood to avoid inhalation. Spills should be handled carefully, and the material safety data sheet (MSDS) should be referred to for specific disposal instructions.