Compound Q&A

How is Imidazo[1,2-a]pyridin-8-ol (CAS: 69214-22-8) typically synthesized?

Answer

Imidazo[1,2-a]pyridin-8-ol
Imidazo[1,2-a]pyridin-8-ol can be synthesized via the condensation of 2-methylpyridine and cyanamide, followed by hydrogenation to reduce the nitrile group. Commonly used catalysts include palladium on carbon, and the yield can be up to 85% with good selectivity.

About

CAS No 69214-22-8
English Name Imidazo[1,2-a]pyridin-8-ol
Molecular Formula C7H6N2O
Molecular Weight 134.14 g/mol
SMILES C1=CN2C=CN=C2C(=C1)O
InChIKey VPUDIWIKGNMSOL-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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