1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Basic Information

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CAS Number

68724-11-8

Molecular Formula

C8H12N2O4

Molecular Weight

200.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

°Cat760mmHg

Density

1.285

Refractive Index

1.517

SMILES

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CC1=CN(C(=O)NC1=O)COCCO

InChI

InChI=1S/C8H12N2O4/c1-6-4-10(5-14-3-2-11)8(13)9-7(6)12/h4,11H,2-3,5H2,1H3,(H,9,12,13)

InChIKey

ATKOZYBRBNGECU-UHFFFAOYSA-N

LogP

-1.1885799999999995

Topological Polar Surface Area

84.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

275

Synonyms & References

English

CCG-117022
1-((2-hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione
DTXSID40218849
1-[(2-OHEtO)Me]T
AKOS001696902
SCHEMBL4088248
1-[(2-hydroxyethoxy)-methyl]-5-methyluracil
N-(2-(Hydroxyethoxy)methyl)-5-methyluracil
2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-methyl-
HMS1617P15
1-(2-hydroxyethoxymethyl)-5-methyl-pyrimidine-2,4-dione
1-[(2-hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Acyclothymidine
CHEMBL11762
ATKOZYBRBNGECU-UHFFFAOYSA-N
1-[(2-Hydroxyethoxy)methyl]-5-methyluracil
SB59420
1-[(2-Hydroxyethoxy)methyl]thymine
68724-11-8
1-(2-hydroxyethoxymethyl)-5-methylpyrimidine-2,4-dione
FT-0641205
1-(2-HYDROXYETHOXY)METHYL-5-METHYLURACIL
1-((2-Hydroxyethoxy)methyl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(2-Hydroxyethoxy)methyl-5-methyluracil
1-<(2-hydroxyethoxy)methyl>-5-methyluracil
1-<(2-hydroxyethoxy)methyl>thymine
5-methyl-1-(2'-hydroxyethoxymethyl)uracil
acyclothymidine

MDL Number

MFCD00457618

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 68724-11-8)?

1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione is a white crystalline solid with a molecular weight of approximately 238.23 g/mol. It has poor solubility in water but is soluble in organic solvents. The compound is relatively stable but can react with strong oxidizing agents. It is often used as a starting material in organic synthesis due to its reactive functional groups.

How is 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 68724-11-8) typically synthesized?

1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione is typically synthesized by the condensation of 2-hydroxyethylamine with 5-methyl-2,4-dione. This reaction is catalyzed by a base such as potassium carbonate, and the yield is generally excellent with high purity. The reaction is carried out in an organic solvent like dimethylformamide (DMF).

What industries use 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 68724-11-8)?

1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione is extensively used in the pharmaceutical industry as a precursor in the synthesis of various drug molecules. It also finds applications in the polymer industry for modifying polymer properties and in the production of semiconductors due to its electronic properties.

What precautions should be taken when handling 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 68724-11-8)?

When handling 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed safety information.