Compound Q&A

How is 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 68724-11-8) typically synthesized?

Answer

1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione is typically synthesized by the condensation of 2-hydroxyethylamine with 5-methyl-2,4-dione. This reaction is catalyzed by a base such as potassium carbonate, and the yield is generally excellent with high purity. The reaction is carried out in an organic solvent like dimethylformamide (DMF).

About

CAS No 68724-11-8
English Name 1-[(2-Hydroxyethoxy)methyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Molecular Formula C8H12N2O4
Molecular Weight 200.19 g/mol
SMILES CC1=CN(C(=O)NC1=O)COCCO
InChIKey ATKOZYBRBNGECU-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:05

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