4-Amino-N-(2-pyrimidinyl)benzenesulfonamide

Basic Information

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CAS Number

68-35-9

Molecular Formula

C10H10N4O2S

Molecular Weight

250.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

253 °C (dec.)

Boiling Point

512.6±52.0°C at 760 mmHg

Density

1.3780 (rough estimate)

Flash Point

263.8 °C

Solubility

Soluble in dimethyl sulfoxide.

Refractive Index

1.6440 (estimate)

SMILES

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Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

InChI

InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

InChIKey

SEEPANYCNGTZFQ-UHFFFAOYSA-N

LogP

0.8596000000000001

Topological Polar Surface Area

97.97 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

327

Safety Information

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GHS Hazard Pictograms

H302

H315

H317

H319

H334

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Sensitiveness

photolabile

Synonyms & References

English

Sulfadiazine
4-amino-N-2-pyrimidinyl
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide
Sulfadiazine zinc salt
Eksadiazine
4-azanyl-N-pyrimidin-2-yl-benzenesulfonamide
Sulfadiazine Base & Sodium
Sulfadiazine,4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide
SULFADIAZINUM
4-Amino-N-pyrimidin-2-ylbenzenesulfonamide
4-Amino-N-pyrimidin-2-yl-benzenesulfonamide
A-306
Adiazin
DEBENAL
Diazin
DIAZYL
PYRIMAL
rp2616
SD-Na
sulphadiazine
Trisem
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
N-(2-Pyrimidinyl)sulfanilamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
N1-(2-Pyrimidinyl)-sulfanilamide
Sulfapyrimidine
Sulfadiazin
Sulfazine
Sulfadiazene
Adiazine
Sulfapyrimidin

MDL Number

MFCD00006065

Customs Code

2935009090

FAQ

What is 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9)?

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) is a sulfonamide compound with the chemical formula C9H10N4O2S. It features a benzene ring substituted with a sulfonamide group (SO2NH) and an amino group at the 4-position, linked to a 2-pyrimidinyl ring. This compound is known for its structural versatility in pharmaceutical and chemical applications.

What are the main uses of 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9)?

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) is widely used in pharmaceuticals as an intermediate in the synthesis of antimicrobial and antifungal agents. It also serves in research for drug development and in industrial processes for creating sulfonamide-based compounds. Its applications are supported by its chemical reactivity and structural adaptability.

Is 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) safe?

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) is generally considered safe when handled according to standard chemical safety protocols. However, it may require protective measures such as gloves and ventilation to minimize exposure. Safety data sheets (SDS) should be consulted for specific handling guidelines and toxicity information.

How should 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) be stored?

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide (CAS: 68-35-9) should be stored in a cool, dry, and dark place, sealed in airtight containers. Avoid exposure to moisture, heat, and direct light to maintain stability. Proper storage ensures its chemical integrity and safety compliance.