6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one

Basic Information

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CAS Number

676515-34-7

Molecular Formula

C8H7BrN2O

Molecular Weight

227.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CNC2=C(C1=O)C=C(C=N2)Br

InChI

InChI=1S/C8H7BrN2O/c9-5-3-6-7(12)1-2-10-8(6)11-4-5/h3-4H,1-2H2,(H,10,11)

InChIKey

ZVCUHOJEMHNZIO-UHFFFAOYSA-N

LogP

1.8423999999999998

Topological Polar Surface Area

41.99 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

198

Synonyms & References

English

AT16221
BCB51534
CS-0130135
6-bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one
6-bromo-1,2,3,4-tetrahydro-1,8-naphthyridin-4-one
6-Bromo-2,8-dihydro-1,8-naphthyridin-4(3H)-one
MFCD12024514
6-BROMO-2,3-DIHYDRO-1H-1,8-NAPHTHYRIDIN-4-ONE
ZVCUHOJEMHNZIO-UHFFFAOYSA-N
AKOS015918943
BS-17330
DTXSID101249123
SCHEMBL6467514
6-bromo-2,3-dihydro-1H-[1,8]naphthyridin-4-one
EN300-6748746
676515-34-7
6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one
6-bromo-2,3-dihydro-1H-1,8-naphthyridin-4-one

MDL Number

MFCD12024514

FAQ

What are the physical and chemical properties of 6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS: 676515-34-7)?

6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one is a solid with a crystalline form. Its molecular weight is approximately 251.04 g/mol. The compound has low aqueous solubility, around 0.01 mg/mL in water. It is known for its reactivity, particularly towards nucleophiles, and can undergo substitution reactions at the bromine atom.

How is 6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS: 676515-34-7) typically synthesized?

6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one can be synthesized via bromination of 2,3-dihydro-1,8-naphthyridin-4(1H)-one. The bromination can be accomplished using N-bromosuccinimide (NBS) in the presence of a suitable radical initiator under UV light or peroxide. The yield is typically around 80-85%, and the reaction is selective towards bromination.

What industries use 6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS: 676515-34-7)?

6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one finds application in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also used in the polymer industry for the modification of polymers and in the electronic industry for the development of organic semiconductors and sensors.

What precautions should be taken when handling 6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS: 676515-34-7)?

When handling 6-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one, it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a fume hood to avoid inhalation. In case of a spill, immediately clean up using appropriate absorbents, and consult the Safety Data Sheet (SDS) for further instructions.