3-Chloro-2-thiophenecarbaldehyde

Basic Information

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CAS Number

67482-48-8

Molecular Formula

C5H3ClOS

Molecular Weight

146.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

98 °C

Density

1.429

Flash Point

230 °C at 760 mmHg

Refractive Index

1.625

SMILES

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C1=CSC(=C1Cl)C=O

InChI

InChI=1S/C5H3ClOS/c6-4-1-2-8-5(4)3-7/h1-3H

InChIKey

PJOJWMNHMJFFCR-UHFFFAOYSA-N

LogP

2.2140000000000004

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

96.4

Synonyms & References

English

2-chloro-3-thiophenecarboxyaldehyde
FT-0654338
AMY10893
Z1198158625
A9039
3-chloro-thiophene-2-carbaldehyde
3-chlorothiophene-2-carbaldehyde
AC-22321
AS-0180
J-512347
DTXSID40370971
EN300-187578
PJOJWMNHMJFFCR-UHFFFAOYSA-N
3-CHLORO-2-THIOPHENECARBOXALDEHYDE
AKOS006229103
2-Thiophenecarboxaldehyde, 3-chloro-
chlorothiophen-2-carbaldehyde
2-formyl-3-chlorothiophene
SCHEMBL1421971
MFCD01764973
3-Chlorothiophene-2-carboxaldehyde
SY064650
CS-0054646
PB32269
67482-48-8
3-Chlorothiophene-2-carbaldehyde
3-Chloro-2-thiophenecarboxaldehyde

MDL Number

MFCD01764973

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8)?

3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8) is a yellow oily liquid. It has a molecular weight of 169.01 g/mol and a boiling point of 237°C. It is slightly soluble in water but readily soluble in organic solvents. The compound is highly reactive and readily forms adducts with nucleophiles.

How is 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8) typically synthesized?

3-Chloro-2-thiophenecarbaldehyde is typically synthesized by the reaction of 2-thiophenecarboxaldehyde with hydrochloric acid. The process involves the nucleophilic substitution of the hydroxyl group with a chloro group. The yield is moderate, and the reaction is usually conducted under mild conditions to avoid side reactions.

What industries use 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8)?

3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for the preparation of various organic compounds. Additionally, it has applications in the polymer industry for the modification of polymers and in the sensor industry for the development of gas sensors.

What precautions should be taken when handling 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8)?

When handling 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully according to the Material Safety Data Sheet (MSDS/SDS). Ensure proper storage in a cool, dry place and avoid contact with water and other reagents.