3-Chloro-2-thiophenecarbaldehyde(CAS: 67482-48-8)

3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8) is a yellow oily liquid. It has a molecular weight of 169.01 g/mol and a boiling point of 237°C. It is slightly soluble in water but readily soluble in organic solvents. The compound is highly reactive and readily forms adducts with nucleophiles.

3-Chloro-2-thiophenecarbaldehyde is typically synthesized by the reaction of 2-thiophenecarboxaldehyde with hydrochloric acid. The process involves the nucleophilic substitution of the hydroxyl group with a chloro group. The yield is moderate, and the reaction is usually conducted under mild conditions to avoid side reactions.

3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for the preparation of various organic compounds. Additionally, it has applications in the polymer industry for the modification of polymers and in the sensor industry for the development of gas sensors.

When handling 3-Chloro-2-thiophenecarbaldehyde (CAS: 67482-48-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully according to the Material Safety Data Sheet (MSDS/SDS). Ensure proper storage in a cool, dry place and avoid contact with water and other reagents.