L-Homoserine | CAS No. 672-15-1

L-Homoserine

Basic Information

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CAS Number

672-15-1

Molecular Formula

C4H9NO3

Molecular Weight

119.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

203 °C (dec.)

Boiling Point

368.7°C at 760 mmHg

Density

1.3126 (rough estimate)

Water Solubility

1100 g/L (30 ºC)

Flash Point

176.8℃

Solubility

1100g/l

Refractive Index

1.4183 (estimate)

Specific Rotation

-8.5 º (c=2, H2O 22 ºC)

SMILES

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C(CO)C(C(=O)O)N

InChI

InChI=1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

InChIKey

UKAUYVFTDYCKQA-VKHMYHEASA-N

LogP

-1.2192999999999998

pKa

2.71(at 25℃)

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

83.4

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

h-hse-oh
s3118
bmse000040
h-hoser-oh
2-amino-4-hydroxy-L-Butyric acid
S-2-AMINO-4-HYDROXYBUTYRIC ACID
NS00079749
L-Homoserine,labeledwith carbon-14(9ci)
672-15-1
Butyric acid, 2-amino-4-hydroxy-, L- (8CI)
2-amino-4-hydroxy-Butyrate
2-amino-4-hydroxybutanoate
DTXSID5075159
HY-W002292
HSE
2-amino-4-hydroxybutyrate
NSC-206251
C00263
2-amino-4-hydroxy-Butyric acid
UNII-6KA95X0IVO
09EC5004-E0F7-4325-B392-59A264DAF51F
CHEMBL11722
Butanoic acid, 2-amino-4-hydroxy-, (S)-
MFCD00063090
AKOS016015443
NSC 206251
(S)-2-Amino-4-hydroxybutanoate
2-amino-4-hydroxy-L-Butyrate
homoserine
Z1172369006
(S)-2-Amino-4-hydroxybutyric acid, Hse

MDL Number

MFCD00063090

Customs Code

29225000

FAQ

What is L-Homoserine (CAS: 672-15-1)?

L-Homoserine is a non-proteinogenic amino acid with the chemical formula C5H11NO3. It is a white crystalline solid, highly soluble in water, and exhibits a pungent odor. This compound plays a key role in biochemical pathways, particularly in the biosynthesis of methionine and cysteine. Its structure is similar to serine but includes an additional methyl group, making it a valuable intermediate in organic chemistry and biotechnology.

What are the main uses of L-Homoserine (CAS: 672-15-1)?

L-Homoserine is primarily used in pharmaceuticals as a precursor for antibiotics like thiamine (vitamin B1) and in the synthesis of other amino acids. In the food industry, it serves as a nutritional supplement and is involved in microbial fermentation processes. It is also utilized in biotech research for studying metabolic engineering and amino acid biosynthesis. Additionally, it finds applications in the production of chiral compounds and as a building block for agricultural chemicals.

Is L-Homoserine (CAS: 672-15-1) safe?

L-Homoserine is generally considered safe when handled properly, with low toxicity in normal use. However, direct contact with skin or inhalation may cause irritation. Safety guidelines recommend wearing protective gloves, goggles, and ensuring adequate ventilation. It is classified under OSHA standards for chemical safety, and long-term exposure should be minimized to avoid potential health risks. Always follow standard laboratory safety protocols when working with this compound.

How should L-Homoserine (CAS: 672-15-1) be stored?

L-Homoserine should be stored in a cool, dry place (ideally below 25°C), away from direct light, and in airtight containers to prevent moisture absorption. It is sensitive to humidity and should be kept in a controlled environment to maintain stability. Storage in glass or HDPE containers is recommended, and the area should be free from strong odors or reactive substances. Proper labeling and storage conditions are essential to ensure safety and longevity.