![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide | CAS No. 66375-96-0
N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide
Basic Information
CAS Number
66375-96-0
Molecular Formula
C21H27N5O4S
Molecular Weight
445.55 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
1.34±0.1 g/cm3 (20 ºC 760 Torr),
Synonyms & References
English
- Glipizide Related Compound C
- 5-Desmethyl-6-methyl Glipizide
- N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-6-methylpyrazine-2-carboxamide
- 1-Cyclohexyl-3-((4-(2-(((6-methylpyrazin-2-yl)carbonyl)amino)ethyl)phenyl)sulfonyl)urea
- 6-methyl-pyrazine-2-carboxylic acid 4-(cyclohexylcarbamoyl-sulfamoyl)-phenethylamide
- FT-0666211
- N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-6-methyl-2-pyrazinecarboxamide
- UNII-G71PN170OW
- N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-6-methylpyrazine-2-carboxamide
MDL Number
MFCD27966017
FAQ
What are the physical and chemical properties of N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide (CAS: 66375-96-0)?
N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is a crystalline solid with a molecular weight of approximately 504.57 g/mol. It has a pKa of around 7.2 and a solubility in water of about 0.01 g/L. The compound is moderately reactive, particularly with nucleophiles and reducing agents. It can be prone to hydrolysis under basic conditions.
How is N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide (CAS: 66375-96-0) typically synthesized?
N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is synthesized through multistep organic reactions, typically involving the coupling of cyclohexylcarbamoyl sulfamide with 2-(4-aminophenyl)ethyl 6-methyl-2-pyrazinecarboxylate. The reaction is often carried out in the presence of a suitable catalyst and requires high purity starting materials to achieve good yield and selectivity.
What industries use N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide (CAS: 66375-96-0)?
N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is primarily used in the pharmaceutical industry for drug development and synthesis of intermediates. It may also have applications in the polymer industry for specific functionalization needs and in the sensor industry for developing chemically sensitive materials.
What precautions should be taken when handling N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide (CAS: 66375-96-0)?
Handling N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide requires appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat. Work should be conducted in a well-ventilated fume hood. In case of spill, it should be contained and cleaned up using appropriate procedures. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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