N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide(CAS: 66375-96-0)

N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is a crystalline solid with a molecular weight of approximately 504.57 g/mol. It has a pKa of around 7.2 and a solubility in water of about 0.01 g/L. The compound is moderately reactive, particularly with nucleophiles and reducing agents. It can be prone to hydrolysis under basic conditions.

N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is synthesized through multistep organic reactions, typically involving the coupling of cyclohexylcarbamoyl sulfamide with 2-(4-aminophenyl)ethyl 6-methyl-2-pyrazinecarboxylate. The reaction is often carried out in the presence of a suitable catalyst and requires high purity starting materials to achieve good yield and selectivity.

N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide is primarily used in the pharmaceutical industry for drug development and synthesis of intermediates. It may also have applications in the polymer industry for specific functionalization needs and in the sensor industry for developing chemically sensitive materials.

Handling N-(2-{4-[(Cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-6-methyl-2-pyrazinecarboxamide requires appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat. Work should be conducted in a well-ventilated fume hood. In case of spill, it should be contained and cleaned up using appropriate procedures. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.