4-Hydroxy-3-methoxy-5-nitrobenzaldehyde

Basic Information

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CAS Number

6635-20-7

Molecular Formula

C8H7NO5

Molecular Weight

197.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

174.0 to 178.0 deg-C

Boiling Point

320.9°C at 760 mmHg

Density

1.5023 (rough estimate)

Refractive Index

1.5700 (estimate)

SMILES

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COC1=CC(=CC(=C1O)[N+](=O)[O-])C=O

InChI

InChI=1S/C8H7NO5/c1-14-7-3-5(4-10)2-6(8(7)11)9(12)13/h2-4,11H,1H3

InChIKey

ZEHYRTJBFMZHCY-UHFFFAOYSA-N

LogP

1.64470

Complexity

226

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

NSC16932
3-nitro-4-hydroxy-5-methoxybenzaldehyde
CHEBI:48385
5-nitrovanilline
NSC-16932
4-Hydroxy-3-methoxy-5-nitrobenzaldehyde #
5-NITRO-4-HYDROXY-3-METHOXYBENZALDEHYDE
G6SQ47R9WB
UNII-G6SQ47R9WB
3-methoxy-4-hydroxy-5-nitrobenzaldehyde
Benzaldehyde, 4-hydroxy-3-methoxy-5-nitro-
GS-3108
5-Nitrovanillin
SCHEMBL344482
NSC35352
AKOS000120593
6635-20-7
NSC-35352
AM20060708
4-hydroxy-5-methoxy-3-nitrobenzaldehyde
NSC 16932
Oprea1_286369
CS-W015680
InChI=1/C8H7NO5/c1-14-7-3-5(4-10)2-6(8(7)11)9(12)13/h2-4,11H,1H
Vanillin, 5-nitro-
NSC 35352
H0728
EN300-17317
4-hydroxy-3-nitro-5-methoxybenzaldehyde
Q27121176
5-nitro vanillin

MDL Number

MFCD00007118

Customs Code

29130000

FAQ

What are the physical and chemical properties of 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7)?

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) is a crystalline compound with a molecular weight of approximately 232.11 g/mol. It has a melting point of 160-162°C and is slightly soluble in water. This compound is known for its reactivity, particularly in electrophilic aromatic substitution reactions and reduction reactions.

How is 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) typically synthesized?

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) can be synthesized through the nitration of 3-methoxy-4-hydroxybenzaldehyde using concentrated nitric acid and sulfuric acid. The reaction is typically carried out under reflux conditions, with the use of a phase transfer catalyst to improve selectivity and yield.

What industries use 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7)?

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the production of dyes and pigments. Additionally, this compound can be used in the development of sensors and as a precursor in semiconductor manufacturing processes.

What precautions should be taken when handling 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7)?

When handling 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using appropriate chemical spill clean-up procedures. Always refer to the safety data sheet (SDS) for detailed guidelines on safe handling and disposal.