Compound Q&A

How is 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) typically synthesized?

Answer

4-Hydroxy-3-methoxy-5-nitrobenzaldehyde
4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (CAS: 6635-20-7) can be synthesized through the nitration of 3-methoxy-4-hydroxybenzaldehyde using concentrated nitric acid and sulfuric acid. The reaction is typically carried out under reflux conditions, with the use of a phase transfer catalyst to improve selectivity and yield.

About

CAS No 6635-20-7
English Name 4-Hydroxy-3-methoxy-5-nitrobenzaldehyde
Molecular Formula C8H7NO5
Molecular Weight 197.14 g/mol
SMILES COC1=CC(=CC(=C1O)[N+](=O)[O-])C=O
InChIKey ZEHYRTJBFMZHCY-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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