2-Chloro-1,3,2-dioxaphospholane 2-oxide

Basic Information

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CAS Number

6609-64-9

Molecular Formula

C2H4ClO3P

Molecular Weight

142.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Insecticides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

12-14 °C (neat)

Boiling Point

91°C/0.8mmHg

Density

1.55 g/mL at 25 °C

Water Solubility

Miscible with water and chloroform.

Refractive Index

n20/D 1.45(lit.)

SMILES

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C1COP(=O)(O1)Cl

InChI

InChI=1S/C2H4ClO3P/c3-7(4)5-1-2-6-7/h1-2H2

InChIKey

SBMUNILHNJLMBF-UHFFFAOYSA-N

LogP

1.3800999999999999

Topological Polar Surface Area

35.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

104

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

Ethylene cycl-chlorophosphate
Q-200255
C2H4ClO3P
6609-64-9
MFCD00043138
2-chloro-1,3,2lambda5-dioxaphospholan-2-one
Ethylene cycl-chlorophosphate (2-chloro-2-oxo-1,3,2-dioxaphospholane);2-Chloro-1,3,2-dioxaphospholane-2-oxide, tech.
Ethylene cycl-chlorophosphate (2-chloro-2-oxo-1,3,2-dioxaphospholane)
2-Chloro-1,3,2-dioxaphospholane-2-oxide (Technical Grade)
FT-0611683
DTXSID70216292
Ethylene glycol chlorophosphate
1,3,2-Dioxaphospholane, 2-chloro-, 2-oxide
2-chloro-1,3-dioxa-2$l^{5}-phosphacyclopentane 2-oxide
Ethylene Chlorophosphate
2-Chloro-2-oxo-1,3,2-dioxaphospholane
1,3,2-Dioxaphospholane,2-chloro-, 2-oxide
A23562
UNII-7EBS5ZK92N
2-Chloro-1,3,2-dioxaphospholane-2-oxide, tech.
2-chloro-1,3,2-dioxaphospholan-2-oxide
2-chloro-1,3,2lambda5-dioxaphospholane 2-oxide
EN300-266546
7EBS5ZK92N
2-Chloro-1,3,2-dioxaphospholane 2-oxide
2-Chloro-1,3,2-dioxaphospholane-2-oxide
EINECS 229-560-6
SCHEMBL169101
NS00035950
AKOS015850823
InChI=1/C2H4ClO3P/c3-7(4)5-1-2-6-7/h1-2H2

MDL Number

MFCD00043138

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9)?

2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9) is a crystalline compound with a molecular weight of approximately 130.53 g/mol. It has a low solubility in water but is soluble in organic solvents like acetone and dimethylformamide. This compound is highly reactive, particularly towards nucleophiles, making it useful in various organic transformations. It is stable under normal conditions but should be stored away from moisture and heat.

How is 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9) typically synthesized?

2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9) is typically synthesized through the reaction of phosphorus oxychloride and 2-hydroxy-1,3-dioxolane. This process involves the substitution of the hydroxyl group by a chlorine atom, followed by the formation of the 2-oxide. The reaction is usually carried out in a solvent like dichloromethane and requires careful control of temperature and reaction conditions to achieve high yield and selectivity.

What industries use 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9)?

2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9) is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also utilized in the polymer industry for the modification of polymers, in the development of sensors for detecting specific chemicals, and in semiconductor manufacturing for etching and cleaning processes.

What precautions should be taken when handling 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9)?

When handling 2-Chloro-1,3,2-dioxaphospholane 2-oxide (CAS: 6609-64-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Storage should be in a cool, dry place away from moisture and other reactive chemicals. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.