2-Bromo-3-pyridinol

Basic Information

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CAS Number

6602-32-0

Molecular Formula

C5H4BrNO

Molecular Weight

174 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

185-188 °C

Boiling Point

321.7℃ at 760 mmHg

Density

1.5643 (rough estimate)

Water Solubility

Soluble in alcohol. Insoluble in water.

Flash Point

148.4℃

Refractive Index

1.5500 (estimate)

SMILES

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C1=CC(=C(N=C1)Br)O

InChI

InChI=1S/C5H4BrNO/c6-5-4(8)2-1-3-7-5/h1-3,8H

InChIKey

YKHQFTANTNMYPP-UHFFFAOYSA-N

LogP

1.5496999999999999

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

78.8

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Bromo-3-hydroxypyridine (2-Bromo-3-pyridinol)
TS-03587
AC-907/30002046
B1478
2-bromo-3-hydroxy-pyridine
EINECS 229-547-5
MFCD00006220
2-bromo-pyridine-3-ol
SY004806
F2147-0555
9DAB85H359
UNII-9DAB85H359
EN300-53585
8N0
2-Bromopyridine-3-ol
2-BROMO-3-HYDROXY PYRIDINE
2-Bromo-pyridin-3-ol
2-Bromopyridin-3-ol
SCHEMBL66814
HY-20026
2-Bromo3-pyridinol
CS-D0714
3-hydroxy-2-bromopyridine
BRN 0109829
PB28951
3-PYRIDINOL, 2-BROMO-
2-Bromo-3-pyridol
DTXSID8022242
Q-102657
InChI=1/C5H4BrNO/c6-5-4(8)2-1-3-7-5/h1-3,8H
NS00047004

MDL Number

MFCD00006220

Customs Code

29333999

FAQ

What are the physical and chemical properties of 2-Bromo-3-pyridinol (CAS: 6602-32-0)?

2-Bromo-3-pyridinol is a crystalline solid with a molecular weight of approximately 188.04 g/mol. It has a low water solubility and good solubility in organic solvents like ethanol and acetone. Chemically, it is moderately reactive and can undergo substitution reactions. It is often used as a starting material in organic synthesis.

How is 2-Bromo-3-pyridinol (CAS: 6602-32-0) typically synthesized?

2-Bromo-3-pyridinol can be synthesized through a bromination reaction of 3-pyridol with N-bromosuccinimide (NBS) in the presence of a suitable solvent like acetonitrile. The reaction is usually conducted in a solution phase with careful control of temperature and reagent stoichiometry to achieve good yield and selectivity.

What industries use 2-Bromo-3-pyridinol (CAS: 6602-32-0)?

2-Bromo-3-pyridinol is utilized in the pharmaceutical industry for the synthesis of complex organic compounds and as an intermediate. It is also used in the production of some polymers and as a reagent in analytical chemistry for sensor applications and semiconductor manufacturing.

What precautions should be taken when handling 2-Bromo-3-pyridinol (CAS: 6602-32-0)?

Proper personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn when handling 2-Bromo-3-pyridinol. Work in a fume hood to minimize exposure. Spills should be handled with caution and cleaned up immediately using appropriate absorbent materials. Always consult the Material Safety Data Sheet (MSDS) for specific safety guidelines.