2-Bromo-3-pyridinol(CAS: 6602-32-0)

2-Bromo-3-pyridinol is a crystalline solid with a molecular weight of approximately 188.04 g/mol. It has a low water solubility and good solubility in organic solvents like ethanol and acetone. Chemically, it is moderately reactive and can undergo substitution reactions. It is often used as a starting material in organic synthesis.

2-Bromo-3-pyridinol can be synthesized through a bromination reaction of 3-pyridol with N-bromosuccinimide (NBS) in the presence of a suitable solvent like acetonitrile. The reaction is usually conducted in a solution phase with careful control of temperature and reagent stoichiometry to achieve good yield and selectivity.

2-Bromo-3-pyridinol is utilized in the pharmaceutical industry for the synthesis of complex organic compounds and as an intermediate. It is also used in the production of some polymers and as a reagent in analytical chemistry for sensor applications and semiconductor manufacturing.

Proper personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn when handling 2-Bromo-3-pyridinol. Work in a fume hood to minimize exposure. Spills should be handled with caution and cleaned up immediately using appropriate absorbent materials. Always consult the Material Safety Data Sheet (MSDS) for specific safety guidelines.