2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (1:1)

Basic Information

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CAS Number

66-83-1

Molecular Formula

C11H15ClN2O

Molecular Weight

226.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

245-250 °C (dec.)

Boiling Point

380 °C at 760 mmHg

Density

1.171

Flash Point

183.6℃

SMILES

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COC1=CC2=C(C=C1)NC=C2CCN.Cl

InChI

InChI=1S/C11H14N2O.ClH/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11;/h2-3,6-7,13H,4-5,12H2,1H3;1H

InChIKey

TXVAYRSEKRMEIF-UHFFFAOYSA-N

LogP

2.0995

Topological Polar Surface Area

51.04 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

186

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Stability

Hygroscopic

Sensitiveness

Hygroscopic

Synonyms & References

English

Tox21_500789
1H-INDOLE-3-ETHANAMINE, 5-METHOXY-, HYDROCHLORIDE (1:1)
F13846
5-Methoxytryptamine HCl
4265IB6QEK
TS-03225
EINECS 241-177-6
5-Methoxytryptamine, HCl
O-Methylserotonin HCl
C11-H14-N2-O.x-Cl-H
INDOLE, 3-(2-AMINOETHYL)-5-METHOXY-, HYDROCHLORIDE
SPECTRUM2300296
5-Methoxytryptamine hydrochloride
1H-Indole-3-ethanamine, 5-methoxy-, hydrochloride
SR-01000076002-1
2-(5-methoxy-1H-indol-3-yl)ethanamine hydrochloride
O-METHYL SEROTONIN HYDROCHLORIDE
3-(2-aminoethyl)-5-methoxyindole HCl
NCGC00094124-01
LP00789
LS-82284
NCGC00094124-02
EU-0100789
5-Methoxy Tryptamine Hcl
UNII-4265IB6QEK
C11H14N2O.xClH
5-Methoxy-1H-indole-3-ethylamine hydrochloride
AM20060707
mono-ethylsuccinate
17107-33-4
DTXSID801017272

MDL Number

MFCD00012684

Customs Code

2933990090

FAQ

What is 2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1)?

2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) is a chemical compound commonly used in pharmaceutical research. Its chemical formula is C12H15NO2·HCl, and it is a white to pale yellow solid with a molecular weight of approximately 259.7 g/mol. The compound is known for its solubility in water and is often used as a building block in the synthesis of various pharmaceutical agents.

What are the main uses of 2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1)?

2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) is primarily used in pharmaceutical applications, particularly in the development of serotonin receptor agonists and antagonists. It serves as an intermediate in the synthesis of drugs targeting mental health conditions, such as antidepressants and anxiolytics. Additionally, it is utilized in research for studying neurochemical pathways and in industrial settings for chemical manufacturing processes.

Is 2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) safe?

2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) is generally considered safe when handled properly. However, it may cause mild irritation to the skin and eyes. Safety precautions include wearing protective gloves, goggles, and a lab coat. It should be used in well-ventilated areas and stored away from incompatible substances to ensure compliance with safety standards.

How should 2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) be stored?

2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride (CAS: 66-83-1) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is important to keep it in a sealed container to prevent moisture absorption and maintain stability. Avoid exposure to light and ensure it is stored away from strong oxidizers and acids to preserve its chemical integrity.