methyl methanesulfonate

Basic Information

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CAS Number

66-27-3

Molecular Formula

C2H6O3S

Molecular Weight

110.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

20°C

Boiling Point

202-203 °C

Density

1.3 g/mL at 25 °C

Water Solubility

200 g/L (20 ºC)

Solubility

200g/l

Refractive Index

n20/D 1.414(lit.)

SMILES

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COS(=O)(=O)C

InChI

InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3

InChIKey

MBABOKRGFJTBAE-UHFFFAOYSA-N

LogP

-0.40759999999999996

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

105

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H350 May cause cancer
Carcinogenicity

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases.

Synonyms & References

English

Methylmesilate
Methyl methanesulfonate, 99%
W-104766
CS-W004702
InChI=1/C2H6O3S/c1-5-6(2,3)4/h1-2H
MFCD00007557
Methanesulfonic acid methyl
Methyl methanesulphonate
Methyl methanesulfonic acid
WLN: WS1&O1
MMS
NSC50256
Z133684226
Methylmethansulfonat
AKOS015900695
CCRIS 396
methanesulfonate methyl
AS-10021
CCG-39749
NCGC00090697-06
Tox21_202094
DTXCID10845
Methyl methansulfonate
KBio3_002251
Methanesulfonic acid, methyl ester (6CI,7CI,8CI,9CI)
NCGC00090697-03
as-Dimethyl sulphite
Spectrum_001850
Methanesulfonic acid methyl ester
NSC-50256
Methyl Methylenesulfonate

MDL Number

MFCD00007557

FAQ

What are the physical and chemical properties of methyl methanesulfonate (CAS: 66-27-3)?

Methyl methanesulfonate (MMs, CAS: 66-27-3) is a colorless to yellow liquid with a slight odor. It has a molecular weight of approximately 120.11 g/mol and a density of about 1.16 g/cm³. It is soluble in water and ethanol. Chemically, it is a strong methylating agent and can react with nucleophilic centers, particularly in DNA. It is primarily used in organic synthesis and mutagenesis studies.

How is methyl methanesulfonate (CAS: 66-27-3) typically synthesized?

Methyl methanesulfonate (MMs, CAS: 66-27-3) can be synthesized by the reaction of methyl bromide with sodium methanesulfonate. The process involves the substitution of a bromine atom on the methyl group of methyl bromide, yielding MMs. This reaction is typically carried out in the presence of an alkaline catalyst and yields a high purity product.

What industries use methyl methanesulfonate (CAS: 66-27-3)?

Methyl methanesulfonate (MMs, CAS: 66-27-3) is primarily used in the pharmaceutical, polymer, and semiconductor industries. It is used as a methylating agent in organic synthesis, as a mutagen in genetic research, and as a crosslinking agent in polymers. Additionally, it is used in the preparation of certain reagents and in the synthesis of other compounds.

What precautions should be taken when handling methyl methanesulfonate (CAS: 66-27-3)?

When handling methyl methanesulfonate (MMs, CAS: 66-27-3), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents. Safety data sheets (SDS) should be consulted for detailed information on handling, storage, and emergency procedures.