methyl methanesulfonate(CAS: 66-27-3)

Methyl methanesulfonate (MMs, CAS: 66-27-3) is a colorless to yellow liquid with a slight odor. It has a molecular weight of approximately 120.11 g/mol and a density of about 1.16 g/cm³. It is soluble in water and ethanol. Chemically, it is a strong methylating agent and can react with nucleophilic centers, particularly in DNA. It is primarily used in organic synthesis and mutagenesis studies.

Methyl methanesulfonate (MMs, CAS: 66-27-3) can be synthesized by the reaction of methyl bromide with sodium methanesulfonate. The process involves the substitution of a bromine atom on the methyl group of methyl bromide, yielding MMs. This reaction is typically carried out in the presence of an alkaline catalyst and yields a high purity product.

Methyl methanesulfonate (MMs, CAS: 66-27-3) is primarily used in the pharmaceutical, polymer, and semiconductor industries. It is used as a methylating agent in organic synthesis, as a mutagen in genetic research, and as a crosslinking agent in polymers. Additionally, it is used in the preparation of certain reagents and in the synthesis of other compounds.

When handling methyl methanesulfonate (MMs, CAS: 66-27-3), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents. Safety data sheets (SDS) should be consulted for detailed information on handling, storage, and emergency procedures.