Romifidine Hydrochloride

Basic Information

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CAS Number

65896-14-2

Molecular Formula

C9H10BrClFN3

Molecular Weight

294.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CN=C(N1)NC2=C(C=CC=C2Br)F.Cl

InChI

InChI=1S/C9H9BrFN3.ClH/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9;/h1-3H,4-5H2,(H2,12,13,14);1H

InChIKey

SDXVSIWCVTYYQN-UHFFFAOYSA-N

LogP

2.3811

Topological Polar Surface Area

36.42 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

234

Synonyms & References

English

1H-Imidazol-2-amine, N-(2-bromo-6-fluorophenyl)-4,5-dihydro-, monohydrochloride
Romifidine Hydrochloride
Romifidine Hydrochlo
N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine,hydrochloride
CS-0134247
AS-78087
HY-119456A
EN300-177542
C9H10BrClFN3
UNII-98LQ6RS0TA
D80881
DTXCID40138593
ROMIFIDINE HYDROCHLORIDE [GREEN BOOK]
Romifidine hydrochloride 100 microg/mL in Acetonitrile
Q27272125
Romifidine hydrochloride
N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine Hydrochloride
MFCD16293882
ROMIFIDINE HYDROCHLORIDE [MI]
N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine;hydrochloride
EX-A4359
SDXVSIWCVTYYQN-UHFFFAOYSA-N
98LQ6RS0TA
ROMIFIDINE HCL
DTXSID80216102
2-(2-Bromo-6-fluoroanilino)-2-imidazoline hydrochloride
65896-14-2
N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amineHydrochloride
Romifidine HCI
Romifidine (hydrochloride)
SCHEMBL1970327

MDL Number

MFCD16293882

FAQ

What are the physical and chemical properties of Romifidine Hydrochloride (CAS: 65896-14-2)?

Romifidine Hydrochloride (CAS: 65896-14-2) is a crystalline compound with a molecular weight of approximately 311.87 g/mol. It is sparingly soluble in water and highly soluble in dilute hydrochloric acid. Chemically, it is known for its basic nature due to the presence of the hydrochloride salt, which reacts with acids to release hydrogen chloride gas.

How is Romifidine Hydrochloride (CAS: 65896-14-2) typically synthesized?

Romifidine Hydrochloride (CAS: 65896-14-2) is synthesized through a multi-step process involving the condensation of a specific aromatic amine with an appropriate carboxylic acid derivative. The reaction is typically performed in the presence of an appropriate base and solvent, followed by treatment with hydrochloric acid to form the hydrochloride salt. The yield and selectivity of the process are influenced by the choice of reagents and reaction conditions.

What industries use Romifidine Hydrochloride (CAS: 65896-14-2)?

Romifidine Hydrochloride (CAS: 65896-14-2) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of pharmaceuticals. It does not have significant applications in other industries like polymers, sensors, or semiconductors.

What precautions should be taken when handling Romifidine Hydrochloride (CAS: 65896-14-2)?

When handling Romifidine Hydrochloride (CAS: 65896-14-2), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a fume hood and away from sources of heat and light. In case of a spill, it should be cleaned up using appropriate absorbent materials in a well-ventilated area. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.