How is Romifidine Hydrochloride (CAS: 65896-14-2) typically synthesized?

Romifidine Hydrochloride (CAS: 65896-14-2) is synthesized through a multi-step process involving the condensation of a specific aromatic amine with an appropriate carboxylic acid derivative. The reaction is typically performed in the presence of an appropriate base and solvent, followed by treatment with hydrochloric acid to form the hydrochloride salt. The yield and selectivity of the process are influenced by the choice of reagents and reaction conditions.