1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione

Basic Information

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CAS Number

65853-65-8

Molecular Formula

C12H10ClNO5

Molecular Weight

283.67 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

103-105 ºC

Density

1.4000 (rough estimate)

Refractive Index

1.6500 (estimate)

SMILES

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C1CC(=O)N(C1=O)OC(=O)OCC2=CC=CC=C2Cl

InChI

InChI=1S/C12H10ClNO5/c13-9-4-2-1-3-8(9)7-18-12(17)19-14-10(15)5-6-11(14)16/h1-4H,5-7H2

InChIKey

LVZHXYXNMHCBKC-UHFFFAOYSA-N

LogP

2.0572

Topological Polar Surface Area

72.91 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

370

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AKOS015850189
N-(2-Chlorobenzyloxycarbonyloxy)succinimide (Z-(2-Cl)-)Su)
65853-65-8
1H-benzimidazole-5-carboxylic
J-509015
(2-chlorophenyl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate
A835251
N-(2-Chlorobenzyloxycarbonyl)succinimide
N-(2-Chlorobenzyloxy carbonyloxy)succinimide
MFCD00010743
LVZHXYXNMHCBKC-UHFFFAOYSA-N
C93500
2-Chlorobenzyl (2,5-dioxopyrrolidin-1-yl) carbonate
AM20040969
2,5-Pyrrolidinedione, 1-[[[(2-chlorophenyl)methoxy]carbonyl]oxy]-
SY051368
SCHEMBL2236423
N-(2-Chlorocarbobenzoxyoxy)succinimide
(2-chlorophenyl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate;N-(2-Chlorobenzyloxycarbonyloxy)succinimide
C12H10ClNO5
N-(2-chlorobenzyloxycarbonyloxy)-succinimide
2-Chlorobenzyl succinimidyl carbonate
AC-10510
N-(O-Chlorocarbobenzoxyoxy)succinimide
N-(2-Chlorobenzyloxycarbonyloxy)succinimide
1-(([(2-Chlorobenzyl)oxy]carbonyl)oxy)-2,5-pyrrolidinedione #
N-(2-Chloro-Z)succinimide
AS-14144
DTXSID70342308
CS-W010033
2-chlorobenzyl 2,5-dioxopyrrolidin-1-yl carbonate

MDL Number

MFCD00010743

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 65853-65-8)?

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is a white or off-white crystalline powder. Its molecular weight is approximately 359.16 g/mol. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It exhibits limited reactivity, but it can undergo hydrolysis under basic conditions. This compound has a melting point of about 220-222°C and a boiling point of around 355-356°C.

How is 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 65853-65-8) typically synthesized?

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is typically synthesized via the condensation of 2-chlorobenzyl chlorophosphate with 2,5-pyrrolidinedione. The reaction is usually carried out in the presence of a base like triethylamine and a solvent like dichloromethane. The yield is generally around 75-85%, with good selectivity towards the desired product.

What industries use 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 65853-65-8)?

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the polymer industry, where it can be used as a monomer or a cross-linking agent. Additionally, it is utilized in the development of sensors and semiconductors for its unique chemical properties.

What precautions should be taken when handling 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 65853-65-8)?

When handling 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential for airborne dispersion. In case of a spill, it should be carefully cleaned up using absorbent materials and disposed of according to local regulations. The safety data sheet (SDS) provides detailed information and guidelines for safe handling and storage.