1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione(CAS: 65853-65-8)

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is a white or off-white crystalline powder. Its molecular weight is approximately 359.16 g/mol. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It exhibits limited reactivity, but it can undergo hydrolysis under basic conditions. This compound has a melting point of about 220-222°C and a boiling point of around 355-356°C.

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is typically synthesized via the condensation of 2-chlorobenzyl chlorophosphate with 2,5-pyrrolidinedione. The reaction is usually carried out in the presence of a base like triethylamine and a solvent like dichloromethane. The yield is generally around 75-85%, with good selectivity towards the desired product.

1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the polymer industry, where it can be used as a monomer or a cross-linking agent. Additionally, it is utilized in the development of sensors and semiconductors for its unique chemical properties.

When handling 1-({[(2-Chlorobenzyl)oxy]carbonyl}oxy)-2,5-pyrrolidinedione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential for airborne dispersion. In case of a spill, it should be carefully cleaned up using absorbent materials and disposed of according to local regulations. The safety data sheet (SDS) provides detailed information and guidelines for safe handling and storage.