1-Methyl-4-(6-nitro-3-pyridinyl)piperazine | CAS No. 657410-79-2
1-Methyl-4-(6-nitro-3-pyridinyl)piperazine
Basic Information
CAS Number
657410-79-2
Molecular Formula
C10H14N4O2
Molecular Weight
222.24 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 1-Methyl-4-(6-nitropyridin-3-yl)piperazine
- 1-methyl-4-(2-nitropyridin-5-yl)piperazine
- 1-methyl-4-(6-nitro-3-pyridyl)piperazine
- 1-Methyl-4-(6-nitro-pyridin-3-yl)-piperazine
- Piperazine, 1-methyl-4-(6-nitro-3-pyridinyl)-
- YVQVMPXTKXNMIV-UHFFFAOYSA-N
- RL04509
- AM804201
- Methyl-4-(6-nitro-pyridin-3-yl)-piperazine
- Y6344
MDL Number
MFCD11520856
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine (CAS: 657410-79-2)?
1-Methyl-4-(6-nitro-3-pyridinyl)piperazine has a white crystalline form. It has a molecular weight of approximately 267.15 g/mol and a solubility of 0.5 g/L in water. It is slightly basic and shows moderate reactivity with strong acids. This compound is not flammable but should be stored in a cool, dry place, away from direct sunlight and heat sources.
How is 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine (CAS: 657410-79-2) typically synthesized?
1-Methyl-4-(6-nitro-3-pyridinyl)piperazine is typically synthesized via the coupling of 6-nitropyridine and 1-methylpiperazine. The reaction is catalyzed by a transition metal such as palladium and is conducted in the presence of a base like cesium carbonate. The yield is generally around 85-90%, and the reaction is performed under inert atmosphere to prevent oxidation.
What industries use 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine (CAS: 657410-79-2)?
1-Methyl-4-(6-nitro-3-pyridinyl)piperazine is primarily used in the pharmaceutical industry as an intermediate for drug development. It is also utilized in the chemical industry for its reactivity and for the production of various compounds with specific functional groups. This compound is less common in other industries like polymers or semiconductors but is critical in the formulation of certain medications and research compounds.
What precautions should be taken when handling 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine (CAS: 657410-79-2)?
When handling 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and used in a fume hood to minimize exposure. In case of a spill, immediately clean up using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for additional guidance. Ensure all waste is disposed of according to local regulations.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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