1-Methyl-4-(6-nitro-3-pyridinyl)piperazine(CAS: 657410-79-2)

1-Methyl-4-(6-nitro-3-pyridinyl)piperazine has a white crystalline form. It has a molecular weight of approximately 267.15 g/mol and a solubility of 0.5 g/L in water. It is slightly basic and shows moderate reactivity with strong acids. This compound is not flammable but should be stored in a cool, dry place, away from direct sunlight and heat sources.

1-Methyl-4-(6-nitro-3-pyridinyl)piperazine is typically synthesized via the coupling of 6-nitropyridine and 1-methylpiperazine. The reaction is catalyzed by a transition metal such as palladium and is conducted in the presence of a base like cesium carbonate. The yield is generally around 85-90%, and the reaction is performed under inert atmosphere to prevent oxidation.

1-Methyl-4-(6-nitro-3-pyridinyl)piperazine is primarily used in the pharmaceutical industry as an intermediate for drug development. It is also utilized in the chemical industry for its reactivity and for the production of various compounds with specific functional groups. This compound is less common in other industries like polymers or semiconductors but is critical in the formulation of certain medications and research compounds.

When handling 1-Methyl-4-(6-nitro-3-pyridinyl)piperazine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and used in a fume hood to minimize exposure. In case of a spill, immediately clean up using appropriate absorbent materials and consult the Safety Data Sheet (SDS) for additional guidance. Ensure all waste is disposed of according to local regulations.