Dipyrido[3,2-c:2',3'-e]pyridazine

Basic Information

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CAS Number

653-05-4

Molecular Formula

C10H6N4

Molecular Weight

182.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

239-240 ºC

Density

1.395±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC2=C(C3=C(C=CC=N3)N=N2)N=C1

InChI

InChI=1S/C10H6N4/c1-3-7-9(11-5-1)10-8(14-13-7)4-2-6-12-10/h1-6H

InChIKey

QMFMZFPFIUREDE-UHFFFAOYSA-N

LogP

1.573

Topological Polar Surface Area

51.56 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

186

Synonyms & References

English

SCHEMBL9058058
4,5,9,10-Tetraazaphenanthrene
FT-0632755
DTXSID90409003
3,8,9,14-tetrazatricyclo[8.4.0.02,7]tetradeca-1(10),2(7),3,5,8,11,13-heptaene
AKOS016013981
Dipyrido[3,2-c:2',3'-e]pyridazine
5,6-Diaza-1,10-Phenanthroline
653-05-4
3,8,9,14-tetrazatricyclo[8.4.0.0^{2,7]tetradeca-1(10),2(7),3,5,8,11,13-heptaene
dipyrido[2,3-a:2',3'-d]pyridazine
Dipyrido[3,2-c:2',3'-e]pyridazine(7CI,8CI,9CI)
1,5,6,10-Tetraazaphenanthren
1,5,6,10-tetraazaphenanthrene

MDL Number

MFCD03013434

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4)?

Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4) is a solid compound. Its molecular weight is approximately 217.15 g/mol. It has a low solubility in water, with a solubility of 0.016 g/100 mL at 25°C. This compound exhibits moderate reactivity, particularly towards nucleophiles. It is insoluble in common organic solvents such as ethanol and acetone but soluble in dimethylformamide (DMF) and dimethyl sulfoxide (DMSO).

How is Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4) typically synthesized?

Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4) is typically synthesized through a multistep reaction involving the condensation of two pyridine derivatives. The process involves the use of concentrated sulfuric acid as a catalyst, with careful control of temperature and reaction time to achieve high selectivity and yield. The product is isolated through recrystallization from a suitable solvent.

What industries use Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4)?

Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4) is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and anticancer drugs. It is also utilized in the production of functional polymers and conductive materials for electronic applications. Additionally, it finds use in the development of gas sensors and as a component in some semiconductors.

What precautions should be taken when handling Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4)?

When handling Dipyrido[3,2-c:2',3'-e]pyridazine (CAS: 653-05-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a chemical fume hood due to its volatility and potential for inhalation. Spills should be cleaned up immediately using an appropriate absorbent material, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.