2-Cyclopropyl-5-pyrimidinecarboxylic acid

Basic Information

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CAS Number

648423-79-4

Molecular Formula

C8H8N2O2

Molecular Weight

164.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Solid

SMILES

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C1CC1C2=NC=C(C=N2)C(=O)O

InChI

InChI=1S/C8H8N2O2/c11-8(12)6-3-9-7(10-4-6)5-1-2-5/h3-5H,1-2H2,(H,11,12)

InChIKey

WWUXGTVYEKCPJQ-UHFFFAOYSA-N

LogP

1.0522

Topological Polar Surface Area

63.08 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

184

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Cyclopropyl-5-pyrimidinecarboxylic acid
2-CYCLOPROPYLPYRIMIDINE-5-CARBOXYLIC ACID
5-Pyrimidinecarboxylic acid, 2-cyclopropyl- (9CI) 2-cyclopropyl-5-pyrimidinecarboxylic acid(SALTDATA: FREE) 2-Cyclopropyl-5-pyrimidinecarboxylic acid
SB57449
GS-6606
SCHEMBL1714095
EN300-243223
2-(Cyclopropyl)pyrimidine-5-carboxylic acid
SY024257
MFCD09054852
5-Pyrimidinecarboxylic acid, 2-cyclopropyl- (9CI)
BB 0238643
FT-0681765
CS-W003589
648423-79-4
DTXSID50630391
Z1013716158
BCP25923
AKOS000301879
2-Cyclopropyl-pyrimidine-5-carboxylic acid
5-pyrimidinecarboxylic acid,2-cyclopropyl-
AMY22658
2-Cyclopropyl-5-pyrimidine carboxylicacid
2-cyclopropylpyrimidine-5-carboxylic acid
5-Pyrimidinecarboxylicacid, 2-cyclopropyl-
C8H8N2O2
BC684648
AB0065646
ST2409955
Z4995
2-(Cyclopr

MDL Number

MFCD09054852

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-Cyclopropyl-5-pyrimidinecarboxylic acid (CAS: 648423-79-4)?

2-Cyclopropyl-5-pyrimidinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 185.17 g/mol. It is slightly soluble in water and more soluble in common organic solvents. The compound exhibits good stability under normal conditions but is reactive towards strong bases and reducing agents.

How is 2-Cyclopropyl-5-pyrimidinecarboxylic acid (CAS: 648423-79-4) typically synthesized?

2-Cyclopropyl-5-pyrimidinecarboxylic acid can be synthesized via the reaction of 5-bromopyrimidine and cyclopropylamine followed by an acid-catalyzed condensation. The reaction typically yields a mixture that requires purification by recrystallization or chromatography.

What industries use 2-Cyclopropyl-5-pyrimidinecarboxylic acid (CAS: 648423-79-4)?

2-Cyclopropyl-5-pyrimidinecarboxylic acid is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry for the development of functional polymers and in the production of certain sensors and semiconductors.

What precautions should be taken when handling 2-Cyclopropyl-5-pyrimidinecarboxylic acid (CAS: 648423-79-4)?

When handling 2-Cyclopropyl-5-pyrimidinecarboxylic acid, it is important to wear proper personal protective equipment (PPE), including gloves and safety glasses. The compound should be stored away from strong bases and reducing agents. In case of a spill, it should be cleaned up with care, following the safety data sheet (SDS) guidelines. Work should be conducted in a well-ventilated area or a fume hood to minimize the risk of inhalation exposure.