N-(7-Hydroxy-1-naphthyl)acetamide

Basic Information

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CAS Number

6470-18-4

Molecular Formula

C12H11NO2

Molecular Weight

201.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

486.2°C at 760 mmHg

Density

1.297 g/cm3

Flash Point

247.9ºC

Refractive Index

1.704

SMILES

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CC(=O)NC1=CC=CC2=C1C=C(C=C2)O

InChI

InChI=1S/C12H11NO2/c1-8(14)13-12-4-2-3-9-5-6-10(15)7-11(9)12/h2-7,15H,1H3,(H,13,14)

InChIKey

ALNWQAFPXMGLTJ-UHFFFAOYSA-N

LogP

2.5038000000000005

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

242

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1-Acetylamino-7-naphthol
N-(7-Hydroxynaphth-1-yl)acetamide
MFCD00035710
NSC7566
n-(7-hydroxynaphthalene-1-yl)-acetamide
8-Acetamido-2-naphthol
SY110480
W-104822
AI3-60059
MLS002638016
1-acetamino-7-hydroxy-naphthalene
EINECS 229-293-5
A19019
NSC 7566
SR-01000513201
Y3Y5XP0GBH
FT-0607289
HMS3093O18
1-Acethyl amino-7 napththol
N-(7-hydroxynaphthyl)acetamide
ALNWQAFPXMGLTJ-UHFFFAOYSA-N
NSC-7566
SCHEMBL1413170
CS-0187548
1-ACETYLAMINO-7-HYDROXYNAPHTHALENE
N-(7-HYDROXY-1-NAPHTHALENYL)ACETAMIDE
UNII-Y3Y5XP0GBH
N-(7-hydroxynaphthalen-1-yl)acetamide
6470-18-4
AKOS003245253
NS00035737

MDL Number

MFCD00035710

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4)?

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is a white crystalline solid with a molecular weight of approximately 212.22 g/mol. It is slightly soluble in water and has a pKa of about 6.0. Chemically, it is stable under normal conditions but can react with strong bases to form its salt. The compound is also sensitive to light and heat, which may affect its stability and reactivity.

How is N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) typically synthesized?

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is typically synthesized by acetylation of 7-hydroxy-1-naphthol using acetic anhydride in the presence of a catalyst like pyridine. The reaction is carried out under mild conditions, and the yield is usually around 85-90%. This method ensures high selectivity and good purity of the product.

What industries use N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4)?

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is used in various industries. It finds applications in pharmaceuticals for its potential as an intermediate in the synthesis of drugs. Additionally, it is used in the production of pigments, dyes, and as a precursor in the manufacturing of electronic materials. Its use in semiconductors and sensors is also emerging due to its unique chemical properties.

What precautions should be taken when handling N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4)?

When handling N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure the use of a fume hood to avoid inhalation of vapors. If a spill occurs, it should be cleaned up immediately using appropriate absorbents and disposing of the waste in a hazardous waste container. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.