N-(7-Hydroxy-1-naphthyl)acetamide(CAS: 6470-18-4)

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is a white crystalline solid with a molecular weight of approximately 212.22 g/mol. It is slightly soluble in water and has a pKa of about 6.0. Chemically, it is stable under normal conditions but can react with strong bases to form its salt. The compound is also sensitive to light and heat, which may affect its stability and reactivity.

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is typically synthesized by acetylation of 7-hydroxy-1-naphthol using acetic anhydride in the presence of a catalyst like pyridine. The reaction is carried out under mild conditions, and the yield is usually around 85-90%. This method ensures high selectivity and good purity of the product.

N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4) is used in various industries. It finds applications in pharmaceuticals for its potential as an intermediate in the synthesis of drugs. Additionally, it is used in the production of pigments, dyes, and as a precursor in the manufacturing of electronic materials. Its use in semiconductors and sensors is also emerging due to its unique chemical properties.

When handling N-(7-Hydroxy-1-naphthyl)acetamide (CAS: 6470-18-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure the use of a fume hood to avoid inhalation of vapors. If a spill occurs, it should be cleaned up immediately using appropriate absorbents and disposing of the waste in a hazardous waste container. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.