Cefotaxime sodium

Basic Information

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CAS Number

64485-93-4

Molecular Formula

C16H16N5NaO7S2

Molecular Weight

477.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

201-210°C

Boiling Point

No data available

Density

1.8000

Water Solubility

Soluble in water.

Flash Point

No data available

Solubility

H2O: aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.soluble

Refractive Index

61 ° (C=1, H2O)

Vapor Pressure

No data available

Specific Rotation

+58.0° +65° (c=1, H2O)

SMILES

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CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

InChI

InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChIKey

AZZMGZXNTDTSME-JUZDKLSSSA-M

LogP

-1.04720

Complexity

839

Safety Information

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GHS Hazard Pictograms

H317

H334

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
KS-1416
AMY40166
C 7912
64485-93-4
NCGC00093734-01
Sodium, Cefotaxime
Cefotaxime and dextrose 2.4% in plastic container
(+)-Cefotaxime sodium salt
AKOS015951272
HMS3712K20
Prestwick_823
C2224
sodium;(6R,7R)-3-(acetyloxymethyl)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EU-0100278
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-, monosodium salt, (6R-(6alpha,7beta(Z)))-
CEFOTAXIME SODIUM (EP IMPURITY)
cefotaxime
Monosodium (6R,7R)-3-acetoxymethyl-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetylamino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
Cefotaxim sodium
HMS2233J21
D00919
NSC 756666
CEFOTAXIME SODIUM [USP MONOGRAPH]
CAS-64485-93-4
CEFOTAXIME SODIUM [EP IMPURITY]
Sodium cefotaxime
CEFOTAXIME SODIUM (USP-RS)
Tox21_110791
HR 756
258J72S7TZ

MDL Number

MFCD00079073

Customs Code

29419000

FAQ

What is Cefotaxime sodium (CAS: 64485-93-4)?

Cefotaxime sodium is a third-generation cephalosporin antibiotic used to treat a variety of bacterial infections. It has the chemical formula C16H16N4O7S2Na and is known for its broad spectrum of activity against gram-positive and gram-negative bacteria. It is typically administered intravenously or intramuscularly and is widely used in clinical settings for its effectiveness and safety profile.

What are the main uses of Cefotaxime sodium (CAS: 64485-93-4)?

Cefotaxime sodium is primarily used in the treatment of severe bacterial infections such as pneumonia, urinary tract infections, and skin infections. It is also employed in hospital settings for infections caused by resistant bacteria. Additionally, it serves as a research compound for studying antibiotic mechanisms and developing new therapeutic strategies.

Is Cefotaxime sodium (CAS: 64485-93-4) safe?

Cefotaxime sodium is generally considered safe when used as directed. However, it may cause side effects such as allergic reactions, gastrointestinal issues, and changes in kidney function. Proper handling and adherence to safety guidelines are essential, particularly in healthcare settings. It is approved by regulatory agencies and meets safety standards for medical use.

How should Cefotaxime sodium (CAS: 64485-93-4) be stored?

Cefotaxime sodium should be stored in a cool, dry place away from light. It is typically kept at a temperature between 2°C to 8°C (refrigerated) and should not be exposed to moisture or direct sunlight. The container must be airtight and labeled properly to ensure stability and prevent contamination.