2-Amino-1-(2,4-difluorophenyl)ethanone

Basic Information

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CAS Number

643029-92-9

Molecular Formula

C8H7F2NO

Molecular Weight

171.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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C1=CC(=C(C=C1F)F)C(=O)CN

InChI

InChI=1S/C8H7F2NO/c9-5-1-2-6(7(10)3-5)8(12)4-11/h1-3H,4,11H2

InChIKey

ZATXLIJNSXGMBG-UHFFFAOYSA-N

LogP

1.1061999999999999

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

174

Synonyms & References

English

2,4-Difluorophenacylamine
MFCD03840509
2-Amino-1-(2,4-difluorophenyl)ethanone
Tetraethyl ammonium tetrafluoroborate
Ethanone, 2-amino-1-(2,4-difluorophenyl)-
Ethanone,2-amino-1-(2,4-difluorophenyl)-
AM1120
CS-0289724
AKOS010296718
2-amino-1-(2,4-difluorophenyl)ethan-1-one
2-Amino-2',4'-difluoroacetophenone
SCHEMBL19104747
DTXSID40476745
FT-0601235
643029-92-9
EN300-1241268
2-AMINO-2',4'-DIFLUOROACETOPHENONE
2Amino2',4'DifluoroAcetophenone

MDL Number

MFCD03840509

FAQ

What are the physical and chemical properties of 2-Amino-1-(2,4-difluorophenyl)ethanone (CAS: 643029-92-9)?

2-Amino-1-(2,4-difluorophenyl)ethanone is a crystalline solid with a molecular weight of approximately 232.09 g/mol. It is soluble in water and organic solvents like ethanol and acetonitrile. Chemically, it is relatively stable but reacts with strong acids and bases. It has a high boiling point and low solubility in non-polar solvents.

How is 2-Amino-1-(2,4-difluorophenyl)ethanone (CAS: 643029-92-9) typically synthesized?

2-Amino-1-(2,4-difluorophenyl)ethanone is typically synthesized via the reaction of 2,4-difluorophenylacetyl chloride with aniline. The synthesis involves the use of a phase transfer catalyst to enhance the reaction efficiency. The yield is generally around 70-80%, and the selectivity is high, with minimal by-products.

What industries use 2-Amino-1-(2,4-difluorophenyl)ethanone (CAS: 643029-92-9)?

2-Amino-1-(2,4-difluorophenyl)ethanone is predominantly used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry, where it can be used as a monomer for producing various materials. Additionally, it is used in the development of sensors and as a precursor in semiconductor manufacturing.

What precautions should be taken when handling 2-Amino-1-(2,4-difluorophenyl)ethanone (CAS: 643029-92-9)?

When handling 2-Amino-1-(2,4-difluorophenyl)ethanone, it is crucial to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.