![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide | CAS No. 639090-55-4
N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide
Basic Information
CAS Number
639090-55-4
Molecular Formula
C18H17ClN6OS
Molecular Weight
400.9 g/mol
AD
Chemical Classification
Basic Physical Properties
Density
1.49
Synonyms & References
English
- N-[4-[4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide
- ULVNROIYQBQKBP-UHFFFAOYSA-N
- AKOS015917797
- yclopropanecarboxylic acid N-[4-[[4-chloro-6-(5-methyl-2H-pyrazol-3-ylamino)pyrimidin-2-yl]sulfanyl]phenyl]amide
- N-[4-[[4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide
- AKOS016011693
- N-(4-(4-chloro-6-(3-methyl-1H-pyrazol-5-ylamino)pyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide
- AC-25063
- CS-0187869
- N-(4-(4-Chloro-6-(3-methyl-1H-pyrazol-5-ylamino)-pyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide
- E76201
- CHEBI:92402
- 639090-55-4
- Q27164141
- N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-chloropyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide
- N-[4-({4-CHLORO-6-[(5-METHYL-1H-PYRAZOL-3-YL)AMINO]PYRIMIDIN-2-YL}SULFANYL)PHENYL]CYCLOPROPANECARBOXAMIDE
- SMR000486400
- HMS2228P13
- A8786
- N-(4-((4-Chloro-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide
- cyclopropane carboxylic acid{4-[4-chloro-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulphanyl]-phenyl}amide
- cyclopropane carboxylic acid{4-[4-chloro-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulphanyl]-phenyl} amide
- FT-0687636
- SCHEMBL648099
- cyclopropane carboxylic acid {4-[4-chloro-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulphanyl]-phenyl}amide
- BS-49776
- DTXSID20647158
- MLS001065627
- CHEMBL1421881
- HMS3358I07
- CYCLOPROPANE CARBOXYLIC ACID {4-[4-CHLORO-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULPHANYL]-PHENYL}AMIDE
MDL Number
MFCD22572707
FAQ
What are the physical and chemical properties of N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide (CAS: 639090-55-4)?
This compound is a crystalline solid with a molecular weight of approximately 509.2 g/mol. It has limited solubility in water but is more soluble in organic solvents like DMSO and DMF. Chemically, it is stable under normal conditions but reacts readily with strong bases. It can be synthesized through various methods, including amidation and sulfuration. The compound is highly reactive due to its sulfur-containing moiety and amide functionality.
How is N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide (CAS: 639090-55-4) typically synthesized?
N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide is typically synthesized through amidation of a sulfide derivative of 4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidine and cyclopropanecarboxylic acid chloride. The reaction is catalyzed by a Lewis acid, resulting in a high yield of the target compound. The process involves careful control of temperature and reaction time to ensure high selectivity and yield.
What industries use N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide (CAS: 639090-55-4)?
This compound is primarily used in the pharmaceutical industry for its potential as an antiviral and antifungal agent. It may also find applications in the polymer industry as a functional monomer or building block for novel materials. Additionally, it could be utilized in the semiconductor industry for its potential as a dopant or in sensor technologies due to its structural and functional characteristics.
What precautions should be taken when handling N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide (CAS: 639090-55-4)?
When handling this compound, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for this compound.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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