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N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide(CAS: 639090-55-4)

N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide
CAS Number

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Basic Information

Molecular Formula
C18H17ClN6OS
Molecular Weight
400.9 g/mol

Physical Properties

Density
1.49

Chemical Identifiers

SMILES
CC1=CC(=NN1)NC2=CC(=NC(=N2)SC3=CC=C(C=C3)NC(=O)C4CC4)Cl
InChIKey
ULVNROIYQBQKBP-UHFFFAOYSA-N

Database References

MDL Number
MFCD22572707

FAQ

This compound is a crystalline solid with a molecular weight of approximately 509.2 g/mol. It has limited solubility in water but is more soluble in organic solvents like DMSO and DMF. Chemically, it is stable under normal conditions but reacts readily with strong bases. It can be synthesized through various methods, including amidation and sulfuration. The compound is highly reactive due to its sulfur-containing moiety and amide functionality.
N-[4-({4-Chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl}sulfanyl)phenyl]cyclopropanecarboxamide is typically synthesized through amidation of a sulfide derivative of 4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidine and cyclopropanecarboxylic acid chloride. The reaction is catalyzed by a Lewis acid, resulting in a high yield of the target compound. The process involves careful control of temperature and reaction time to ensure high selectivity and yield.
This compound is primarily used in the pharmaceutical industry for its potential as an antiviral and antifungal agent. It may also find applications in the polymer industry as a functional monomer or building block for novel materials. Additionally, it could be utilized in the semiconductor industry for its potential as a dopant or in sensor technologies due to its structural and functional characteristics.
When handling this compound, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for this compound.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Contact Person

Jin Jinle (National Unified Telephone Line)

Email

hnjjlchem@126.com

Telephone

10106090

Address

Changsha Kaifu District Tongtai Street Zhongshan Road 589 Kaifu Wangdawei Square C District 3rd Office Building 2905