Cyclohexyl(diphenyl)phosphine

Basic Information

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CAS Number

6372-42-5

Molecular Formula

C18H21P

Molecular Weight

268.34 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

59.0 to 62.0 deg-C

Boiling Point

374°C at 760 mmHg

SMILES

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C1CCC(CC1)P(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChI=1S/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2

InChIKey

ZXKWUYWWVSKKQZ-UHFFFAOYSA-N

LogP

4.4520000000000035

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

226

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

6SW83V2X43
Diphenylphosphinocyclohexane
Cyclohexyldiphenylphosphine
C18H21P
cyclohexyldiphenylphosphane
NS00021286
BCP05539
DTXSID6074671
FT-0636122
MFCD00046360
A834487
J-520171
Cyclohexyl diphenyl phosphine
SCHEMBL34871
ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
cyclohexyl(diphenyl)phosphane
HY-W013327
Diphenylcyclohexylphosphine
ZXKWUYWWVSKKQZ-UHFFFAOYSA-
SY036763
cyclohexyl-di(phenyl)phosphane
EINECS 228-904-2
Phosphine, cyclohexyldiphenyl-
CS-W014043
InChI=1/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2
AMY11717
AKOS015840834
AS-59019
6372-42-5
CYCLOHEXYL-DIPHENYL-PHOSPHANE
Cyclohexyldiphenylphosphine, 98%

MDL Number

MFCD00046360

Customs Code

2902909090

FAQ

What are the physical and chemical properties of Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5)?

Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) is a colorless to pale yellow liquid. It has a molecular weight of approximately 298.23 g/mol and a boiling point of 144-145°C. The compound has low solubility in water but is highly soluble in organic solvents. It is moderately reactive and can undergo various organic transformations, including substitution reactions.

How is Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) typically synthesized?

Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) is commonly synthesized by the reaction of cyclohexyl chloride with diphenylphosphine in the presence of a base such as potassium carbonate. The reaction is typically carried out in an inert solvent like toluene or dimethylformamide (DMF) to enhance solubility and yield. The process involves the nucleophilic substitution of the chloride ion by the diphenylphosphine ligand.

What industries use Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5)?

Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) is used in various industries, particularly in the pharmaceutical and polymer sectors. It serves as a ligand in transition metal catalysis, enhancing reactivity and selectivity in organic synthesis. Additionally, it is used in the production of semiconductors and as a sensor component for detecting specific chemical species.

What precautions should be taken when handling Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5)?

When handling Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the safety data sheet (SDS) for specific handling and disposal instructions.