Compound Q&A
How is Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) typically synthesized?
Answer
Cyclohexyl(diphenyl)phosphine (CAS: 6372-42-5) is commonly synthesized by the reaction of cyclohexyl chloride with diphenylphosphine in the presence of a base such as potassium carbonate. The reaction is typically carried out in an inert solvent like toluene or dimethylformamide (DMF) to enhance solubility and yield. The process involves the nucleophilic substitution of the chloride ion by the diphenylphosphine ligand.
About
CAS No
6372-42-5
English Name
Cyclohexyl(diphenyl)phosphine
Molecular Formula
C18H21P
Molecular Weight
268.34 g/mol
SMILES
C1CCC(CC1)P(C2=CC=CC=C2)C3=CC=CC=C3
InChIKey
ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
