2,3-dimethoxyaniline

Basic Information

View in Editor

CAS Number

6299-67-8

Molecular Formula

C8H11NO2

Molecular Weight

153.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Yellow to Brown Liquid

Boiling Point

93°C/1.4mmHg

Density

1,14 g/cm3

Flash Point

250.1°Cat760mmHg

Refractive Index

1.5630-1.5650

SMILES

View in Editor

COC1=CC=CC(=C1OC)N

InChI

InChI=1S/C8H11NO2/c1-10-7-5-3-4-6(9)8(7)11-2/h3-5H,9H2,1-2H3

InChIKey

HEZIOZBMPKPOER-UHFFFAOYSA-N

LogP

1.2859999999999998

Topological Polar Surface Area

44.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

119

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Sensitive to air, light, and heat

Synonyms & References

English

2,3-dimethoxy-phenylamine
CS-W016280
6299-67-8
SB75740
EN300-99105
AKOS000314057
FT-0648042
AS-10695
2,3-Dimethoxyaniline
NSC-44873
6-methoxy-2-amino anisole
Benzenamine, 2,3-dimethoxy-
NSC44873
MFCD00180769
J-507027
(2,3-dimethoxyphenyl)amine
2,3-dimethoxyaniline, AldrichCPR
2,3-bis(methyloxy)aniline
SY030638
2,3-Dimethoxyaniline #
Amino-brenzkatechin-dimethylather
BB 0257834
AMY28016
D2284
InChI=1/C8H11NO2/c1-10-7-5-3-4-6(9)8(7)11-2/h3-5H,9H2,1-2H3
HEZIOZBMPKPOER-UHFFFAOYSA-
SCHEMBL210128
DTXSID30286335
F5608-0070
(2,3-Dimethoxyphenyl)amine
HEZIOZBMPKPOER-UHFFFAOYSA-N

MDL Number

MFCD27756373

Customs Code

2922299090

FAQ

What regulatory guidelines apply to 2,3-dimethoxyaniline (CAS: 6299-67-8)?

2,3-Dimethoxyaniline (CAS: 6299-67-8) falls under the scope of various regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it is classified as a skin and eye irritant. In Europe, it is regulated under the REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation, which requires specific documentation and safety data sheets. Additionally, it is subject to FDA and EPA regulations in the United States, which include stringent handling, storage, and disposal requirements to protect public health and the environment.

Are there alternatives to 2,3-dimethoxyaniline (CAS: 6299-67-8) in synthesis?

Several alternatives to 2,3-dimethoxyaniline (CAS: 6299-67-8) are available in synthesis, including 2-methoxyaniline, 3-methoxyaniline, and their isomers. These compounds can serve similar functional roles in organic reactions. Other substitute solutions include using protected methoxy groups in intermediate steps, which can reduce the need for direct methoxy substitution in the final product.

What is the market or research trend for 2,3-dimethoxyaniline (CAS: 6299-67-8)?

The market for 2,3-dimethoxyaniline (CAS: 6299-67-8) is primarily driven by its applications in the pharmaceutical and agrochemical industries. Research trends indicate a growing interest in the development of new analogs with enhanced bioavailability and reduced toxicity. The trend also includes the exploration of its use in the synthesis of dyes and pigments, where its unique properties make it a valuable intermediate. Market analysis suggests steady demand, with potential for growth in emerging research fields focused on green chemistry and sustainable processes.

How should waste containing 2,3-dimethoxyaniline (CAS: 6299-67-8) be handled?

Waste containing 2,3-dimethoxyaniline (CAS: 6299-67-8) should be handled with caution to minimize environmental impact. Waste collection should be done in appropriate containers, and the waste should be properly labeled. Disposal should follow strict environmental regulations, typically involving incineration or hazardous waste facilities. Safety measures include the use of personal protective equipment (PPE) and adherence to local waste disposal guidelines to ensure compliance with regulatory standards and environmental protection policies.