7-Iodo-1-indanone

Basic Information

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CAS Number

628732-02-5

Molecular Formula

C9H7IO

Molecular Weight

258.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CC(=O)C2=C1C=CC=C2I

InChI

InChI=1S/C9H7IO/c10-7-3-1-2-6-4-5-8(11)9(6)7/h1-3H,4-5H2

InChIKey

NKVIZRKBYNZSAX-UHFFFAOYSA-N

LogP

2.4201000000000006

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

178

Synonyms & References

English

7-IODO-1-INDANONE
2,3-Dihydro-7-iodoinden-1-one
DTXSID70464115
AKOS015853712
FT-0646406
7-iodo-2,3-dihydroinden-1-one
7-iodoindan-1-one
EN300-2204246
1H-Inden-1-one, 2,3-dihydro-7-iodo-
7-iodo-2,3-dihydro-1H-inden-1-one
SCHEMBL1339854
CS-0001935
A834056
1H-Inden-1-one,2,3-dihydro-7-iodo-
628732-02-5
7-Iodo-1-Indanone

MDL Number

MFCD09744084

FAQ

What are the physical and chemical properties of 7-Iodo-1-indanone (CAS: 628732-02-5)?

7-Iodo-1-indanone (CAS: 628732-02-5) is a crystalline solid with a molecular weight of approximately 236.06 g/mol. It is moderately soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions involving the iodo group. It is generally stable under neutral and slightly acidic conditions but should be handled with caution due to its reactivity.

How is 7-Iodo-1-indanone (CAS: 628732-02-5) typically synthesized?

7-Iodo-1-indanone (CAS: 628732-02-5) can be synthesized through the iodination of 1-indanone using N-bromosuccinimide (NBS) in the presence of a radical initiator such as AIBN. Common solvents include dichloromethane or acetonitrile, and the reaction typically involves stirring the mixture at room temperature. The yield can be enhanced by optimizing the reaction conditions, such as solvent choice and temperature.

What industries use 7-Iodo-1-indanone (CAS: 628732-02-5)?

7-Iodo-1-indanone (CAS: 628732-02-5) is primarily used in the pharmaceutical and sensor industries. It serves as a key intermediate in the synthesis of certain medicinal compounds and has applications in analytical chemistry for the development of sensors and detection methods. Its unique functional groups make it valuable for various chemical transformations and derivatizations.

What precautions should be taken when handling 7-Iodo-1-indanone (CAS: 628732-02-5)?

When handling 7-Iodo-1-indanone (CAS: 628732-02-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. This compound should be handled in a well-ventilated area or fume hood due to its potential reactivity. Spills should be carefully managed, and the Material Safety Data Sheet (MSDS) should be consulted for specific spill procedures. Storage should be in a cool, dry place away from direct sunlight and incompatible materials.