7-Iodo-1-indanone(CAS: 628732-02-5)

7-Iodo-1-indanone (CAS: 628732-02-5) is a crystalline solid with a molecular weight of approximately 236.06 g/mol. It is moderately soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions involving the iodo group. It is generally stable under neutral and slightly acidic conditions but should be handled with caution due to its reactivity.

7-Iodo-1-indanone (CAS: 628732-02-5) can be synthesized through the iodination of 1-indanone using N-bromosuccinimide (NBS) in the presence of a radical initiator such as AIBN. Common solvents include dichloromethane or acetonitrile, and the reaction typically involves stirring the mixture at room temperature. The yield can be enhanced by optimizing the reaction conditions, such as solvent choice and temperature.

7-Iodo-1-indanone (CAS: 628732-02-5) is primarily used in the pharmaceutical and sensor industries. It serves as a key intermediate in the synthesis of certain medicinal compounds and has applications in analytical chemistry for the development of sensors and detection methods. Its unique functional groups make it valuable for various chemical transformations and derivatizations.

When handling 7-Iodo-1-indanone (CAS: 628732-02-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. This compound should be handled in a well-ventilated area or fume hood due to its potential reactivity. Spills should be carefully managed, and the Material Safety Data Sheet (MSDS) should be consulted for specific spill procedures. Storage should be in a cool, dry place away from direct sunlight and incompatible materials.