L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid | CAS No. 62568-57-4

L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid

Basic Information

CAS Number

62568-57-4

Molecular Formula

C35H48N10O15

Molecular Weight

848.82 g/mol

AD

Basic Physical Properties

Density

1.458±0.06 g/cm3 (20 ºC 760 Torr),

Water Solubility

Soluble in water at 0.5mg/ml

C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)N

InChI

InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1

InChIKey

ZRZROXNBKJAOKB-GFVHOAGBSA-N

LogP

-5.733500000000017

Topological Polar Surface Area

406.73999999999995 Ų

Hydrogen Bond Donor/Acceptor

15 / 25

Synonyms & References

English

  • Deltasleep-inducing peptide (rabbit)
  • Delta Sleep Inducing Peptide
  • Delta-Sleep Inducing Peptide
  • Delta-Sleep Inducing Peptide, DSIP, Emideltide
  • DSIP
  • EMIDELTIDE
  • SLEEP INDUCING PEPTIDE
  • TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU
  • TRP-ALA-GLY-GLY-ASP-ALA-SER: PO3H2-GLY-GLU [WAGGDA-S: PO3H2-GE]
  • TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU
  • WAGGDASGE
  • DSIP nonapeptide
  • L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid
  • δ-Sleep Inducing Peptide

MDL Number

MFCD00076883

FAQ

What are the physical and chemical properties of L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid (CAS: 62568-57-4)?

L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid is a crystalline compound with a molecular weight of approximately 1039.54 Da. It has a solubility of 10 mg/mL in water. Chemically, it is relatively stable but can undergo hydrolysis under acidic or alkaline conditions. The compound has limited reactivity under normal conditions, but caution should be exercised during synthesis and storage.

How is L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid (CAS: 62568-57-4) typically synthesized?

L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid is typically synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves stepwise coupling of protected amino acids, with each addition requiring careful deprotection and activation steps. High-yield and high-selectivity are achieved through the use of appropriate coupling reagents and optimized reaction conditions.

What industries use L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid (CAS: 62568-57-4)?

L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid finds applications in the pharmaceutical industry, where it is used as a component in the development of peptides and peptidomimetics. It may also be used in the manufacturing of certain polymers and sensors, though its use in semiconductors is less common.

What precautions should be taken when handling L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid (CAS: 62568-57-4)?

When handling L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid, safety goggles and gloves should be worn, and work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials, and proper disposal procedures should be followed. For more detailed safety information, refer to the Safety Data Sheet (SDS) for this compound.

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