Compound Q&A
How is L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid (CAS: 62568-57-4) typically synthesized?
Answer
L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid is typically synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves stepwise coupling of protected amino acids, with each addition requiring careful deprotection and activation steps. High-yield and high-selectivity are achieved through the use of appropriate coupling reagents and optimized reaction conditions.
About
CAS No
62568-57-4
English Name
L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid
Molecular Formula
C35H48N10O15
Molecular Weight
848.824 g/mol
SMILES
C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)N
InChIKey
ZRZROXNBKJAOKB-GFVHOAGBSA-N
Last Updated: 2025-10-07 19:42
