2-Chloro-3-(trifluoromethyl)aniline

Basic Information

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CAS Number

62476-58-8

Molecular Formula

C7H5ClF3N

Molecular Weight

195.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

25-28℃

Boiling Point

217.5±40.0 ºC (760 Torr),

Density

1.425±0.06 g/cm3 (20 ºC 760 Torr),

Water Solubility

Insoluble in water.

Flash Point

85.3±27.3 ºC,

Refractive Index

1.5

SMILES

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C1=CC(=C(C(=C1)N)Cl)C(F)(F)F

InChI

InChI=1S/C7H5ClF3N/c8-6-4(7(9,10)11)2-1-3-5(6)12/h1-3H,12H2

InChIKey

WLXOMMTWPMQFDE-UHFFFAOYSA-N

LogP

2.9410000000000007

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

159

Safety Information

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GHS Hazard Pictograms

H311

H302

H332

H315

H319

Hazard Statement

H311 Toxic in contact with skin
Acute toxicity, dermal

H302 Harmful if swallowed
Acute toxicity, oral

H332 Harmful if inhaled
Acute toxicity, inhalation

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

(2-Chloro-3-trifluoromethylphenyl)amine
3-Amino-2-chlorobenzotrifluoride
Benzenamine, 2-chloro-3-(trifluoromethyl)-
DTXSID10407243
DS-15578
SY032035
SCHEMBL3289893
CS-0017878
2-chloro-3-(trifluoromethyl)aniline
MFCD04115988
EN300-7392399
62476-58-8
BCP11239
2-chloro-3-(trifluoromethyl)benzenamine
FT-0735757
AKOS015956696
2-Chloro-3-(trifluoromethyl)aniline
WLXOMMTWPMQFDE-UHFFFAOYSA-N
SBB091924
2-chloro-3-trifluoromethyl-phenylamine
AS06948
FCH1121545
2-chloro-3-(trifluoromethyl)phenylamine
PC30302

MDL Number

MFCD04115988

Customs Code

2921420090

FAQ

What regulatory guidelines apply to 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8)?

2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) falls under the GHS classification as a hazardous chemical due to its corrosive properties. Regulatory guidelines include OSHA PPE requirements, EPA environmental regulations, and REACH for European manufacturers and importers. FDA guidelines may also apply for its use in specific applications, such as in pharmaceuticals.

Are there alternatives to 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) in synthesis?

Alternatives to 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) in synthesis include 2-Amino-3-(trifluoromethyl)aniline and 2-Chloro-3-(trifluoromethyl)benzene. These can serve as effective substitutes depending on the specific reaction conditions and desired end product.

What is the market or research trend for 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8)?

Market trends for 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) show increased research interest in its use as an intermediate in the synthesis of pharmaceuticals and dyes. Prices remain stable, but the trend indicates growing demand, especially in the pharmaceutical industry. Recent studies focus on optimizing synthesis methods and identifying safer alternatives.

How should waste containing 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) be handled?

Waste containing 2-Chloro-3-(trifluoromethyl)aniline (CAS: 62476-58-8) should be collected in appropriate containers and stored separately. Incineration is a common method of disposal, but professional waste disposal services are recommended. Environmental protection measures include proper handling to prevent soil and water contamination, and compliance with local regulations regarding hazardous waste management is essential.