2,6-Dimethoxypyridine

Basic Information

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CAS Number

6231-18-1

Molecular Formula

C7H9NO2

Molecular Weight

139.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

179°C

Density

1.053 g/mL at 25 °C

Refractive Index

n20/D 1.503(lit.)

SMILES

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COC1=NC(=CC=C1)OC

InChI

InChI=1S/C7H9NO2/c1-9-6-4-3-5-7(8-6)10-2/h3-5H,1-2H3

InChIKey

IBTGEEMBZJBBSH-UHFFFAOYSA-N

LogP

1.0987999999999998

Topological Polar Surface Area

31.35 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

87.6

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3.2 Class 3.2

Synonyms & References

English

DTXSID00871156
EINECS 228-334-4
122797-02-8
W-105013
F1905-7031
SCHEMBL160602
DS-13432
2,6-Dimethoxy-pyridine
AKOS007930318
Pyridine, 2,6-dimethoxy-
A8611
FT-0610681
2,6-Dimethoxypyridine
2,6-Dimethoxypyridine, 98%
F11261
D1918
Z1255423468
MFCD00006266
6231-18-1
AM62344
EN300-223948
2,6-Dimethoxy pyridine
Pyridine, 2,6-dimethoxy-, radical ion(1+) (9CI)
CS-W018314
InChI=1/C7H9NO2/c1-9-6-4-3-5-7(8-6)10-2/h3-5H,1-2H
NS00044340
2,6-Dimethoxypyridin
Pyridine,2,6-dimethoxy

MDL Number

MFCD00006266

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,6-Dimethoxypyridine (CAS: 6231-18-1)?

2,6-Dimethoxypyridine (CAS: 6231-18-1) is a yellow crystalline compound with a molecular weight of approximately 168.17 g/mol. It has a low solubility in water but is soluble in common organic solvents such as ethanol and acetone. Chemically, it is relatively stable but can react with strong acids and bases. It is a Lewis base and can participate in complexation reactions.

How is 2,6-Dimethoxypyridine (CAS: 6231-18-1) typically synthesized?

2,6-Dimethoxypyridine is typically synthesized by the methylation of 2,6-pyridinedicarboxylic acid with dimethyl sulfate. The reaction is conducted in an organic solvent such as toluene and in the presence of a base like sodium hydroxide. The yield is generally around 70-80%, with selectivity for the desired product.

What industries use 2,6-Dimethoxypyridine (CAS: 6231-18-1)?

2,6-Dimethoxypyridine (CAS: 6231-18-1) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for the development of functional materials, and sensors for detecting specific chemical species. It is also employed in the production of semiconductors due to its ability to act as a dopant.

What precautions should be taken when handling 2,6-Dimethoxypyridine (CAS: 6231-18-1)?

When handling 2,6-Dimethoxypyridine (CAS: 6231-18-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it is recommended to sweep it up carefully and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.