Compound Q&A

How is 2,6-Dimethoxypyridine (CAS: 6231-18-1) typically synthesized?

Answer

2,6-Dimethoxypyridine
2,6-Dimethoxypyridine is typically synthesized by the methylation of 2,6-pyridinedicarboxylic acid with dimethyl sulfate. The reaction is conducted in an organic solvent such as toluene and in the presence of a base like sodium hydroxide. The yield is generally around 70-80%, with selectivity for the desired product.

About

CAS No 6231-18-1
English Name 2,6-Dimethoxypyridine
Molecular Formula C7H9NO2
Molecular Weight 139.15399999999997 g/mol
SMILES COC1=NC(=CC=C1)OC
InChIKey IBTGEEMBZJBBSH-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21

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