(S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate | CAS No. 62284-79-1

(S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate

Basic Information

CAS Number

62284-79-1

Molecular Formula

C13H13BrN2O4S

Molecular Weight

528.22 g/mol

AD

Basic Physical Properties

Melting Point

192 °C (dec.)

Boiling Point

388.6°C at 760 mmHg

Flash Point

87℃

OC(=O)C(O)=O.BrC1=CC=C(C=C1)C1(CN2CCSC2=N1)C1=CC=C(Br)C=C1

InChI

InChI=1S/C17H14Br2N2S.C2H2O4/c18-14-5-1-12(2-6-14)17(13-3-7-15(19)8-4-13)11-21-9-10-22-16(21)20-17;3-1(4)2(5)6/h1-8H,9-11H2;(H,3,4)(H,5,6)

InChIKey

BAGHEDBDFJEONB-UHFFFAOYSA-N

LogP

4.029200000000003

Topological Polar Surface Area

90.19999999999999 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

345

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

  • (-)-4-Bromotetramisole oxalate
  • (S)-(-)-4-Bromotetramisole Oxalate
  • (-)-p-Bromotetramisole Oxalate
  • (?)-4-Bromotetramisole oxalate
  • (-)-4-bromotetramisole oxalate salt
  • (-)-P-BROMOLEVAMISOLE OXALATE
  • (-)-P-BROMOTETRAMISOLE OXALATE SALT
  • 6-BROMOLEVAMISOLE OXALATE
  • L-P-BROMOTETRAMISOLE OXALATE
  • S(-)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate
  • -p-Bromotetramisole oxalate
  • 6-Bromolevamisole oxalate

MDL Number

MFCD00070406

FAQ

What are the physical and chemical properties of (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1)?

The (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1) is a crystalline solid with a molecular weight of approximately 360.03 g/mol. It has a high solubility in organic solvents like dimethylformamide and dimethyl sulfoxide but is insoluble in water. The compound is moderately reactive, particularly in acidic environments. It is stable under normal storage conditions but should be stored away from moisture and oxidizing agents.

How is (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1) typically synthesized?

The (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate is typically synthesized through a multi-step process involving bromination of an aromatic ring, followed by coupling with an imidazole derivative. The reaction is catalyzed by a palladium-based catalyst under microwave-assisted conditions. The overall yield is generally around 70-80%, with good selectivity towards the desired enantiomer.

What industries use (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1)?

The (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1) is primarily used in the pharmaceutical industry for its potential as a drug intermediate. It is also explored in the polymer industry for its ability to enhance material properties and in sensor technology for its reactivity. Additionally, it shows promise in the semiconductor industry for its electronic properties.

What precautions should be taken when handling (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1)?

When handling (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate, it is crucial to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood or a laboratory with proper exhaust systems. Spills should be handled carefully with appropriate absorbent materials, and the area should be cleaned with water and neutralizing agents. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information.

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