Compound Q&A
How is (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate (CAS: 62284-79-1) typically synthesized?
Answer
![(S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate](https://static.chemtradehub.com/structs/622/62284-79-1-a701.webp "(S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate")
The (S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate is typically synthesized through a multi-step process involving bromination of an aromatic ring, followed by coupling with an imidazole derivative. The reaction is catalyzed by a palladium-based catalyst under microwave-assisted conditions. The overall yield is generally around 70-80%, with good selectivity towards the desired enantiomer.
About
CAS No
62284-79-1
English Name
(S)-6-(4-Bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Oxalate
Molecular Formula
C13H13BrN2O4S
Molecular Weight
528.22 g/mol
SMILES
OC(=O)C(O)=O.BrC1=CC=C(C=C1)C1(CN2CCSC2=N1)C1=CC=C(Br)C=C1
InChIKey
BAGHEDBDFJEONB-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
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