4-Bromo-2-pyridinecarbonitrile

Basic Information

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CAS Number

62150-45-2

Molecular Formula

C6H3BrN2

Molecular Weight

183.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

87-93°C

Boiling Point

265.3℃ at 760 mmHg

Density

1.726

Flash Point

114.257℃

Refractive Index

1.612

SMILES

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C1=CN=C(C=C1Br)C#N

InChI

InChI=1S/C6H3BrN2/c7-5-1-2-9-6(3-5)4-8/h1-3H

InChIKey

CZXDCTUSFIKLIJ-UHFFFAOYSA-N

LogP

1.71578

Complexity

137

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

SCHEMBL504885
J-400564
F3099-7184
EN300-102445
4-bromopyridine-2-carbonitrile
4-Bromo-2-cyano-pyridine
CS-W019598
SY015416
VU0509242-1
A15705
4-Bromo-2-cyanopyridine
FT-0600164
MFCD04065805
AKOS000275960
AM20061382
BCP27215
4-BROMO-2-PYRIDINECARBONITRILE
4-BROMO-PYRIDINE-2-CARBONITRILE
AC-9582
CZXDCTUSFIKLIJ-UHFFFAOYSA-N
DTXSID40351205
PS-3946
62150-45-2
2-Pyridinecarbonitrile, 4-bromo-
PB29307
CHEMBL4563874
4-bromopicolinonitrile
4-Bromopyridine-2-carbonitrile
4-Bromopicolinonitrile
4-Bromo-2-Cyanopyridine
PubChem23829

MDL Number

MFCD04065805

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2)?

4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) is a crystalline solid with a molecular weight of approximately 203.03 g/mol. It is slightly soluble in water but has good solubility in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can react with strong bases and oxidizing agents. It is a useful intermediate in organic synthesis.

How is 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) typically synthesized?

4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) can be synthesized via the reaction of 2-pyridinecarbonitrile with bromine in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like acetonitrile. The yield is typically around 70-80%, with good selectivity towards the brominated product.

What industries use 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2)?

4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) is primarily used as an intermediate in the pharmaceutical industry, particularly in the synthesis of certain drugs. It also finds applications in the polymer industry for the production of various functional polymers, and in the sensor industry for the development of chemical sensors and detectors.

What precautions should be taken when handling 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2)?

When handling 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Proper disposal of waste should follow local regulations, and spills should be cleaned up immediately using appropriate chemicals. Always refer to the Safety Data Sheet (SDS) for specific handling and safety guidelines.