Compound Q&A

How is 4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) typically synthesized?

Answer

4-Bromo-2-pyridinecarbonitrile
4-Bromo-2-pyridinecarbonitrile (CAS: 62150-45-2) can be synthesized via the reaction of 2-pyridinecarbonitrile with bromine in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like acetonitrile. The yield is typically around 70-80%, with good selectivity towards the brominated product.

About

CAS No 62150-45-2
English Name 4-Bromo-2-pyridinecarbonitrile
Molecular Formula C6H3BrN2
Molecular Weight 183.01 g/mol
SMILES C1=CN=C(C=C1Br)C#N
InChIKey CZXDCTUSFIKLIJ-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55

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